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hiv 1 nef in 1

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
HIV-1 Nef-IN-1
T903913728-56-8
HIV-1 Nef-IN-1 is an inhibitor of the HIV-1 Nef protein, effectively competing for Nef-SH3Hck interactions (Kd: 6.7 μM).
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Hck-IN-1
T115381473404-51-1
Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for wild-type HIV-1 replication.
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