hemostatic

Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.

Hematin (Ferrihemic acid) is an iron-containing porphyrin. It is used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.

Ethamsylate (Dicynene) usually is used as a hemostatic drug, which increases capillary endothelial resistance and platelet adhesion, and inhibits biosynthesis and action of prostaglandins.

Adrenalone hydrochloride (Adrenalone HCl) is a dopamine β-oxidase inhibitor with a similar structure to the norepinephrine transporter (NET) ligand, with an IC50 of 36.9 μM. It is an adrenergic agonist that acts as a local vasoconstrictor and hemostatic agent.

Carbazochrome (Adchnon) is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. It is hoped that this drug can be used in the future for preventing excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on its effectiveness and the severity of possible side effects remains to be fairly inconclusive. Carbazochrome has been investigated for use in the treatment of hemorrhoids in a mixture with troxerutin.

Menaquinone-4 (Vitamin K2) is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis.

SphK1&2-IN-1, a sphingosine kinase inhibitor, exhibits anti-inflammatory, antitumor, and hemostatic properties.

Esculamine is a compound known for its hemostatic, vasodilatory, and anti-inflammatory properties.

Spiclamine (Epsilamine) is a hemostatic agent.

Ethyl 10-bromodecanoate is an anti-inflammatory and hemostatic agent. As a member of the linoleic acid family, Ethyl 10-bromodecanoate also exhibits antibacterial properties.

Mecrylate polymerizes in contact with moisture. It is used as a tissue adhesive. It also has higher homologs have hemostatic and antibacterial properties.

Naftazone is a vasoprotectant drug used for hemostasis. Naftazone is shown to accelerate human saphenous vein endothelial cell proliferation in vitro at concentrations which did not alter the hemostatic balance.

Dicresulene diammonium is an impurity found in Policresulen, which is an organic acid possessing hemostatic, antimicrobial, and antiviral properties[1][2].

Fitusiran (ALN-AT3SC) is a small interfering RNA therapeutic designed to selectively bind antithrombin messenger RNA in the liver, leading to sustained reduction of antithrombin production and enhanced thrombin generation, thereby offering a mechanistically innovative research approach for restoring hemostatic balance in hemophilia models.

Hydrastinine, a key alkaloid component found in Hydrastis canadensis (goldenseal), serves as an effective hemostatic agent.

Dencichine (ODAP) is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effect, it could significantly prevent the progression of diabetic nephropathy possibly attribute to down-regulation of the TGF-β/Smad pathway and rebalance the deposition and degradation of ECM proteins.

Carbazochrome (Standard) is the standard substance of Carbazochrome, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Carbazochrome (Adchnon) is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. It is hoped that this drug can be used in the future for preventing excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on its effectiveness and the severity of possible side effects remains to be fairly inconclusive. Carbazochrome has been investigated for use in the treatment of hemorrhoids in a mixture with troxerutin.

Menaquinone-4 (Standard) is a reference standard for research and analysis in studies involving Menaquinone-4. Menaquinone-4 (Vitamin K2) is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis.

Phloyoside II is a iridoid glucosides natural product isolated from shanzhiside, which is believed to possess hemostatic and cardiovascular protective properties.

Lagochiline, a diterpene compound, serves as a promising hemostatic agent and can be extracted from plants belonging to the Lagochilus species [1] [2].

Ornipressin Acetate (POR-8) is a potent vasoconstrictor, hemostatic and renal agent.

Bemiltenase alfa is a hemostatic agent that targets coagulation factor X (FX). It activates FX to facilitate the conversion of prothrombin into thrombin, which subsequently transforms fibrinogen into fibrin, thereby forming a stable blood clot and exerting its hemostatic effect. Bemiltenase alfa shows potential for research in bleeding symptoms associated with hemophilia.

Nonacog gamma is a coagulation factor IX (FIX) supplement that activates factor X (FX), facilitating the generation of thrombin, which then converts fibrinogen into fibrin to form a stable blood clot and exert hemostatic effects. Nonacog gamma holds potential for research in the treatment of hemophilia B.

Agkistrodon Haemocoagulase, a thrombin protein derived from the pit viper Agkistrodon, is utilized as a hemostatic compound.