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Results for "
gw-583340 dihydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists1
GW583340 dihydrochloride
T228271173023-85-2In house
GW 583340 dihydrochloride is a potent and orally available dual EGFR ErbB2 (epidermal growth factor receptor tyrosine kinase) inhibitor and is capable of reversing ABCG2- and ABCB1-mediated resistance.GW 583340 dihydrochloride selectively inhibits the growth of human tumor cells overexpressing EGFR and ErbB2, selectively inhibits the growth of human tumor cells overexpressing EGFR and ErbB2, and inhibits 80% of tumor growth in a mouse xenograft model, with potential anticancer activity.
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