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gr-85548a

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
  • Isotope Products
    1
    TargetMol | Isotope_Products
Naratriptan
T8666121679-13-8
Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.
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Naratriptan D3 Hydrochloride
GR-85548A D3
T121761190021-64-7
Naratriptan D3 Hydrochloride, the deuterium-labeled form of Naratriptan, is a selective agonist of the 5-HT1 receptor subtype.
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Naratriptan hydrochloride
Naratriptan HCl, Amerge, Naramig, GR-85548A hydrochloride
T6602143388-64-1
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydrochloride) binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D 1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.
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