gp-45840

Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.

Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac-D4 sodium is the deuterated form of Diclofenac sodium (T1555). Diclofenac Sodium (GP 45840) is an effective, non-selective anti-inflammatory agent that acts as a COX inhibitor, with IC50 values of 4 nM for human COX-1 and 1.3 nM for COX-2 in CHO cells. For sheep COX-1 and COX-2, the IC50 values are 5.1 μM and 0.84 μM, respectively. Diclofenac Sodium induces apoptosis in neural stem cells by activating the caspase cascade [apoptosis].

Diclofenac sodium (Standard) is the reference standard of diclofenac sodium, suitable for quantitative analysis, quality control, biochemical experiments, and related research. Diclofenac sodium is a non-selective anti-inflammatory drug and a cyclooxygenase (COX) inhibitor. In CHO cells, its IC₅₀ values against human COX-1 and COX-2 are 4 nM and 1.3 nM, respectively; against ovine COX-1 and COX-2, they are 5.1 μM and 0.84 μM, respectively. In addition, diclofenac sodium induces apoptosis in neural stem cells by activating the caspase cascade.