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(2)
By Target- Beta Amyloid
- Glutaminyl Cyclase(1)
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Results for "
glutaminyl cyclase inhibitor 1
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Glutaminyl Cyclase Inhibitor 1T114242110449-60-8In houseGlutaminyl Cyclase Inhibitor 1, a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM, can be utilized for studying neurological disorders.
- $122
SizeQTY - SEN177SEN-177, SEN 177T610632117405-13-5SEN177 demonstrates potential utility in investigations involving Huntington’s disease and functions as a potent inhibitor of glutaminyl cyclase (QPCT), exhibiting an IC50 value of 0.013 μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces early-stage mutant HTT oligomerization and decreases the percentage of neurons containing Q80 aggregates. SEN177 is therefore relevant for neurodegenerative disease research, protein aggregation biology, and glutaminyl cyclase-associated molecular pathways.
- $34
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