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(2)
By Target- Apoptosis
- Autophagy(2)
- PI3K(2)
- DNA-PK(1)
- PROTACs(1)
- SGK(1)
- mTOR(1)
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Results for "
gdc0941
" in TargetMol Product Catalog- Inhibitors & Agonists3
- PROTAC Products1
Pictilisib
Cited
RG7321, GDC-0941
T1994957054-30-7
Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3 33 3 75 nM for p110α β δ γ).
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CitedPictilisib dimethanesulfonate
GDC-0941 dimethanesulfonate, GDC-0941 2 MeSO3H salt
T11381957054-33-0
Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).
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PROTAC SGK3 degrader-1
SGK3-PROTAC1
T138472381320-35-8
PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, inducing degradation of endogenous SGK3. It inhibits GDC0941-induced proliferation of cancer cells. [5017-88-83-4]
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