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Results for "
gdc 6036
" in TargetMol Product Catalog- Inhibitors & Agonists3
divarasib
GDC-6036
T99722417987-45-0
Divarasib (GDC-6036) (GDC-6036) is an investigational, oral, high-potency and selective KRAS G12C inhibitor with an IC50 of < 0.01 μM. Divarasib irreversibly locks KRAS G12C oncoprotein in an inactive state and inhibits tumor cell growth. It is being investigated for use in solid tumors, including non-small cell lung and colorectal cancers and other types of cancer.
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GDC-6036-NH
T640212417918-80-8
GDC-6036-NH is a precursor of Compound 17a b, which is a RAS inhibitor and can be used in cancer research.
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Divarasib adipate
GDC-6036 adipate
T862802762240-36-6
Divarasib (GDC-6036) adipate is a selective and highly potent KRAS G12C inhibitor with an impressively low IC 50 value of <0.01 μM, designed for oral administration. It covalently attaches to the switch II (SW-II) pocket in KRAS G12C, irreversibly maintaining the protein in its inactive GDP-bound state [1] [2].
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