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(2)
By Target- Transferase
- Apoptosis(1)
- Ras(1)
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By Target By ResearchField- Cancer(2)
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Results for "
fti 277 hydrochloride
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- FTI-277 hydrochlorideFTI 277 HClT2700180977-34-8FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than the closely related GGTase I.
- $48
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Cited - FTI-277FTI277, FTI 277T62675170006-73-2FTI-277 hydrochloride is a farnesyl transferase inhibitor and highly potent Ras CAAX peptidomimetic that antagonizes both H-Ras and K-Ras oncogenic signaling pathways, FTI-277 hydrochloride additionally inhibits hepatitis delta virus infection, making it a valuable compound for studying Ras-driven oncogenesis, protein prenylation, and antiviral intervention strategies.
- $196
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