fluoxetine

Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity.

Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.

Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.

Fluoxetine-Conjugated Platinum(IV) prodrug-1 is an eEF2K inhibitor that can hinder the proliferation of cancer cells, induce DNA damage, and cause cell cycle arrest at the S phase, leading to apoptosis (Apoptosis). It also promotes the accumulation of reactive oxygen species (ROS) and disrupts mitochondrial function. This prodrug inhibits the migration and invasion of TNBC cells by suppressing MMP-2 activity and induces autophagy in TNBC cells through AMPK activation. In the 4T1-Luc mouse model, it exhibits antitumor activity and triggers immune suppression. Fluoxetine-Conjugated Platinum(IV) prodrug-1 is relevant for research in triple-negative breast cancer (TNBC).

Fluoxetine oxalate is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.

Fluoxetine succinate ester is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.

N-Nitroso fluoxetine is a derivative of fluoxetine.1It is genotoxic toS. typhimuriumwhen used at concentrations ranging from 0.06 to 0.12 mg/ml.

meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.

(±)-Fluoxetine-D4 Oxalate is a deuterated compound of  (±)-Fluoxetine Oxalate (T71389). (±)-Fluoxetine Oxalate has a CAS number of 114414-02-7.

Fluoxetine-d6oxalate (LY-110140-d6oxalate) is the deuterium-labeled version of Fluoxetine oxalate, which functions as a selective serotonin reuptake inhibitor (SSRI).

Fluoxetine (Standard) is the standard substance of Fluoxetine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity.

(±)-Fluoxetine-D4 Oxalate (Standard) is a reference standard of (±)-Fluoxetine-D4 Oxalate intended for quantitative analysis, quality control, and related biochemical research applications. (±)-Fluoxetine-d4 Oxalate is a deuterated compound of (±)-Fluoxetine Oxalate. (±)-Fluoxetine Oxalate has a CAS number of 114414-02-7.

DB03417 is a compound listed in web page: https://go.drugbank.com/drugs/DB03417. DB03417 is a potential tryptase inhibitor.

Norfluoxetine-D5 hydrochloride is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewater effluent.

Norfluoxetine-D5 hydrochloride is a deuterated compound of Norfluoxetine Hydrochloride. Norfluoxetine Hydrochloride (T21029) has a CAS number of 57226-68-3. Norfluoxetine hydrochloride is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.

Norfluoxetine Hydrochloride (Standard) is a reference standard for research and analysis in studies involving Norfluoxetine Hydrochloride. Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.

Norfluoxetine-D5 Hcl (Standard) is a reference standard of Norfluoxetine-D5 Hcl intended for quantitative analysis, quality control, and related biochemical research applications. Norfluoxetine-d5 is used as an internal standard when quantitatively analyzing norfluoxetine by gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry. Norfluoxetine is the active metabolite of the antidepressant fluoxetine. It is generated from fluoxetine by the cytochrome P450 (CYP) subtypes CYP2C9, CYP2C19, and CYP3A.

(S)-Norfluoxetine, the S enantiomer of Norfluoxetine, functions as a selective serotonin reuptake inhibitor. It enhances allopregnanolone levels and reduces aggression in socially isolated mice.

(R)-Norfluoxetine is the (R)-enantiomer of Norfluoxetine. It functions as a potent serotonin reuptake inhibitor, with a Ki value of 13 nM. This compound is utilized in the research of depression.

Norfluoxetine, the active metabolite of the antidepressant Fluoxetine, acts as a selective inhibitor for serotonin uptake.

Seproxetine HCl, a more active enantiomer of N-desmethyl metabolite fluoxetine, works by selectively inhibiting the serotonin uptake carrier.

Pentoxifylline-D6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent. It increases the deformability of washed isolated human erythrocytes when used at a concentration of 100 µM. Pentoxifylline (1, 2, and 3 mM) inhibits ADP-induced platelet aggregation in isolated human whole blood. It inhibits thrombus formation induced by ADP in a hamster cheek pouch model when administered at doses of 5, 10, and 20 mg/kg. Formulations containing pentoxifylline have been used in the treatment of intermittent claudication.

Seganserin, a non-selective 5-hydroxytryptamine 2-HT receptor antagonist, reversed the inhibitory effects of fluoxetine and quipazine on luteinizing hormone-induced hyperphagia, depression and nociception, and reversed the antidepressant and analgesic effects induced by fluoxetine and quipazine.

M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM.