flunarizine

Flunarizine is an orally administered peripheral vasodilator, acting as a dual blocker of voltage-gated Na+/Ca2+ channels and a D2 dopamine receptor antagonist, exhibiting anti-migraine activity.

Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihydrochloride (R14950) is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.

(Z)-Flunarizine is the Z isomer of Flunarizine. It functions as an effective dual blocker of Na+/Ca2+ (T-type) channels and acts as a D2 dopamine receptor antagonist. Flunarizine possesses anticonvulsant and antimigraine properties, in addition to promoting peripheral vasodilation.

Flunarizine (Standard) is the standard substance of Flunarizine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Flunarizine is a non-selective calcium entry blocker and a histamine H1 receptor blocker. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.