expansion

Edicotinib (JNJ-527) is a blood-brain-penetrating, orally active, selective CSF-1R inhibitor (IC50 value is 3.2 nM), with less inhibitory effects on KIT (IC50 value is 20 nM) and FLT3 (IC50 value is 190 nM). Edicotinib (JNJ-527) can block microglial proliferation and attenuate neurodegeneration, and can be used to study Alzheimer's disease and rheumatoid arthritis.

IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions, and so on.

Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.

LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S with IC50 values ​​of 7.7 and 1.67 nM for human and mouse cathepsin S, respectively. LY 3000328 (Cathepsin S inhibitor) may slow or prevent abdominal aortic aneurysm (AAA) expansion and/or reduce the risk of AAA rupture by inhibiting cathepsin S-mediated degradation of extracellular matrix proteins, elastin and collagen.

7-Azaindole-4-carboxylic acid ,with CAS No. 479553-01-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Azaindole-4-carboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-Benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ,with CAS No. 189089-90-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-Benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid ,with CAS No. 1067193-34-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ,with CAS No. 800402-07-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Azetidine-1,2-dicarboxylic acid 1-tert-butyl ester2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER, ,with CAS No. 159749-28-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Azetidine-1,2-dicarboxylic acid 1-tert-butyl ester provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Tert-butyl cis-3-hydroxymethylcyclobutylcarbamate ,with CAS No. 142733-64-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Tert-butyl cis-3-hydroxymethylcyclobutylcarbamate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-(4-Bromophenyl)cyclopropanecarboxylic acid ,with CAS No. 345965-52-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-(4-Bromophenyl)cyclopropanecarboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(1R,5S,6R)-3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid ,with CAS No. 927679-54-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (1R,5S,6R)-3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(S)-tert-butyl 5-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide ,with CAS No. 396074-50-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (S)-tert-butyl 5-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ethyl ester ,with CAS No. 117642-16-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ethyl ester provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Amino-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester ,with CAS No. 171049-41-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Amino-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2,2-Dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one ,with CAS No. 20348-21-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2,2-Dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-Bromo-1,4-dihydro-2H-3,1-benzoxazin-2-one ,with CAS No. 1017783-09-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Bromo-1,4-dihydro-2H-3,1-benzoxazin-2-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylic acid 6-tert butyl ester 3-ethyl ester ,with CAS No. 193537-14-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylic acid 6-tert butyl ester 3-ethyl ester provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Methylphenylsulfonylurea ,with CAS No. 1694-06-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Methylphenylsulfonylurea provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Tert-butyl 4-(1-hydroxycyclopropanecarbonyl)piperazine-1-carboxylate ,with CAS No. 1788054-84-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Tert-butyl 4-(1-hydroxycyclopropanecarbonyl)piperazine-1-carboxylate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-Boc-2-methylpiperazine ,with CAS No. 120737-78-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-Boc-2-methylpiperazine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(R)-1-Boc-3-(hydroxymethyl)piperazine ,with CAS No. 278788-66-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (R)-1-Boc-3-(hydroxymethyl)piperazine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5N-Boc-3-amino-4,6-dihydro-1H-pyrrolo[3,4-c]pyrozole ,with CAS No. 398491-59-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5N-Boc-3-amino-4,6-dihydro-1H-pyrrolo[3,4-c]pyrozole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid, 4,6-dihydro-, 1,1-dimethylethyl ester ,with CAS No. 657428-42-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid, 4,6-dihydro-, 1,1-dimethylethyl ester provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.