ehrlich ascites tumor

Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.

2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.This compound is unstable in powder form and other related salt forms are recommended.

2-Hydroxystearic acid is a hydroxy fatty acid found in humans and U. armoricana. It reduces the growth of Ehrlich ascites tumor (EAT) cells in vitro when used at a concentration of 100 μM.

Saframycin S, an antibiotic featuring a Racemomycin group, demonstrates inhibitory effects against Ehrlich ascites tumor. The LD50 value of Saframycin S in ddY mice is 3.2 mg/kg (i.p.).

MU147 is an MRE11 nuclease inhibitor and chemical probe with anticancer properties, exhibiting lethal effects on Ehrlich ascites tumor cells both in vivo and in vitro. It disrupts the MRE11 nuclease-dependent double-strand break repair mechanism without impairing ATM activation. Additionally, MU147 damages the degradation of nascent strands at stalled replication forks and selectively affects BRCA2-deficient cells.

2,3-Dihydroxybutanoic acid is an anticancer agent extracted from the leaves of Corydalis plants. It exhibits anticancer activity both in vivo and in vitro and has a lethal effect on Ehrlich ascites tumor cells.

Manninotrionate is an antitumor compound. Manninotrionate was coupled to BSA and an antiserum to this compound-protein coupling was prepared in rabbits. The antiserum did not agglutinate Ehrlich ascites tumor cells, which have been shown to contain cell surface glycoproteins with alpha-D-galactosyl end groups.

Pilatin exhibits inhibitory effects on both bacteria and fungi, and it strongly suppresses the incorporation of thymidine and uridine into DNA and RNA in Ehrlich ascites tumor cells.

Vinleurosine can partially inhibit the energy dependent transport of alpha-aminoisobutyric acid in Ehrlich ascites tumor cells.