e260

E260 (Fer and FerT inhibitor) is a Fer/FerT kinase inhibitor

Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.

Kobe2601 is a water-soluble structural analog of Kobe0065. Kobe2601 inhibits Ras-Raf binding. Kobe2601 can be used as a chemical probe to study the inhibitory mechanisms of Ras family proteins.

Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.

Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme).2 Benastatin B also inhibits the transglycosylase activity of A. baumannii, C. difficile, E. coli, and S. aureus recombinant penicillin-binding proteins (PBPs; IC50s = 16, 53.3, 30.7, and 31.6 µM, respectively).3 It is active against several bacteria, including methicillin-resistant S. aureus (MRSA; MIC = 3.12 µg/ml).