dspe-peg-maleimide

DSPE-PEG-Maleimide (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DSPE-PEG-Maleimide is a useful organic compound for research related to life sciences and the catalog number is T64567.

DSPE-PEG-Maleimide (MW 2000) is a PEG compound which composed of DSPE and maleimide groups. DSPE-PEG-Maleimide (MW 2000) can be used for compose liposomes [1] .

DSPE-PEG(2000) maleimide is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE). This compound is frequently utilized both in vitro and in vivo for synthesizing lipid nanoparticles (LNPs) that deliver siRNA or small molecule anticancer drugs. In experiments, LNPs containing DSPE-PEG(2000) maleimide and encapsulating siRNA targeting the mRNAs for p53 and K-RAS induced tumor regression in a PANC-1 pancreatic ductal adenocarcinoma mouse xenograft model.

DSPE-PEG-SH (MW 2000), a pegylated phospholipid featuring a reactive thiol group for forming covalent thioether linkages with maleimide, is an amphiphilic polymer capable of self-assembling into lipid bilayers in aqueous solutions. It is utilized in encapsulating agents within drug delivery systems, including mRNA vaccines.

DSPE-PEG-Maleimide, a compound comprised of DSPE phospholipid and maleimide, is utilized for preparing nanostructured lipid carriers, enhancing both blood circulation time and stability of encapsulated agents [1] [2]. The variant DSPE-PEG5000-Mal includes PEG5000, further contributing to its utility in drug delivery systems.

DSPE-PEG-Maleimide features DSPE phospholipids and maleimide for the preparation of nano-structured lipid carriers. It enhances the stability of encapsulated active molecules and prolongs circulation time in the bloodstream.

DSPE-PEG2000-Maleimide is a PEG compound composed of DSPE and a maleimide group. This compound is applicable in the construction of liposomes.

DSPE-PEG-SH, MW 3400, is a maleimide-reactive PEG lipid. This amphiphilic polymer can form lipid bilayers in water and is utilized in the creation of liposomes. It serves as a drug nanocarrier for delivering mRNA, DNA, or siRNA. Reagent grade, intended for research purposes only.