dspe-peg-maleimide

DSPE-PEG-Maleimide (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DSPE-PEG-Maleimide is a useful organic compound for research related to life sciences and the catalog number is T64567.

DSPE-PEG-Maleimide (MW 2000) is a PEG compound which composed of DSPE and maleimide groups. DSPE-PEG-Maleimide (MW 2000) can be used for compose liposomes [1] .

DSPE-PEG-Maleimide (MW 3400) ammonium combines DSPE phospholipids with maleimide for the preparation of nanostructured lipid carriers. It is applicable in drug delivery research.

DSPE-PEG-Maleimide (ammonium) (MW 2000) is a compound containing DSPE phospholipids and maleimide, designed for the preparation of nanoscale lipid carriers. It is applicable in the study of drug delivery systems.

DSPE-PEG(2000) maleimide is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE). This compound is frequently utilized both in vitro and in vivo for synthesizing lipid nanoparticles (LNPs) that deliver siRNA or small molecule anticancer drugs. In experiments, LNPs containing DSPE-PEG(2000) maleimide and encapsulating siRNA targeting the mRNAs for p53 and K-RAS induced tumor regression in a PANC-1 pancreatic ductal adenocarcinoma mouse xenograft model.

DSPE-PEG-SH (MW 2000) is a polyethylene glycol-modified phospholipid with a terminal reactive thiol group capable of forming covalent thioether linkages with Maleimide-containing molecules. DSPE-PEG-SH (MW 2000) self-assembles into amphiphilic lipid bilayers in aqueous solutions and is employed in drug delivery research, including the encapsulation of nucleic acids, peptides, and small molecules, as well as in mRNA vaccine formulations.

DSPE-PEG5000-Mal ammonium is an amphiphilic conjugate composed of DSPE phospholipid and a maleimide functional group, commonly utilized in the preparation of nanostructured lipid carriers for drug delivery applications. DSPE-PEG5000-Mal ammonium enhances both systemic circulation time and colloidal stability of encapsulated therapeutic agents, and its variant DSPE-PEG5000-Mal incorporates a PEG5000 chain to further improve pharmacokinetic properties and biocompatibility in nanomedicine formulations.

DSPE-PEG-Maleimide features DSPE phospholipids and maleimide for the preparation of nano-structured lipid carriers. It enhances the stability of encapsulated active molecules and prolongs circulation time in the bloodstream.

DSPE-PEG2000-Maleimide is a PEG compound composed of DSPE and a maleimide group. This compound is applicable in the construction of liposomes.

DSPE-PEG-SH, MW 3400, is a maleimide-reactive PEG lipid. This amphiphilic polymer can form lipid bilayers in water and is utilized in the creation of liposomes. It serves as a drug nanocarrier for delivering mRNA, DNA, or siRNA. Reagent grade, intended for research purposes only.