direct blue-1

Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and operates as a potent, competitive VGLUT inhibitor, not impacting plasma membrane transporters. This compound stands out as the inaugural small molecule PrP ligand to inhibit Aβ binding.

Direct Blue 108, a triphenyl two oxazine compound, is utilized for dyeing cotton, viscose fiber, silk, and their blended fabrics [1].

Direct Blue 86 (Solvent Blue 38), a dye known for its role in the staining of myelin sheaths, is frequently used in microscopy to identify demyelination within the central nervous system. Additionally, this compound serves various commercial purposes, including dyeing cotton and mucilage glue fabrics [1].