dihydrouracil

5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.

2-Methoxyphenyl dihydrouracil-azaspiro[5.5]undecane-C-PIP is an E3 ligase ligand-linker conjugate designed for the synthesis of PROTACSOS1 degrader-10.

Dihydrouracil-Ph-2-Me-piperidine is an E3 ligase ligand used in the synthesis of [PROTACHPK1 Degrader-6].

Dihydrouracil-Ph-piperazine-Boc is an E3 ligase ligand-linker conjugate that includes a CRBN-based ligand and linker, suitable for PROTAC synthesis.

3-Hydroxypropanoic acid-pip-hydroquinone-dihydrouracil is a crucial intermediate in the synthesis of the complete PROTACHPK1 Degrader-2, serving as a conjugate (conjugate) of E3 ligase ligand and linker.

5,6-Dihydrouracil-D4 is the deuterated form of 5,6-Dihydrouracil (T4886). Dihydrouracil itself is a metabolite of uracil and serves as a marker for identifying deficiencies in dihydropyrimidine dehydrogenase (DPD).

5,6-dihydro-5-Fluorouracil (5-FUH2) is an inactive metabolite of 5-FU and can be used for the study of organismal metabolism.

β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.

Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in uracil metabolism, produced from dihydrouracil by the enzyme dihydropyrimidase and further decomposed to beta-alanine by beta-ureidopropionase. It is a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with severe toxicity to the antineoplastic agent 5-fluorouracil.

β-Alanine (Standard) is a reference standard for research and analysis in studies involving β-Alanine. β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.

EndonucleaseVIII is a DNA repair enzyme capable of excising oxidized pyrimidines from DNA. As a bacterial DNA glycosylase/AP lyase, EndonucleaseVIII can remove modified pyrimidines, including thymine glycol (Tg), uracil glycol, dihydrothymine, and dihydrouracil (DHU).