digitoxin

Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).

Acetyldigitoxin is a derivative of lanatoside A or of DIGITOXIN and can be used for fast digitalization in congestive heart failure.

Digoxin-OVA is a hapten-carrier protein conjugate formed by coupling Digoxin to chicken ovalbumin (OVA). As a hapten, Digoxin alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. Digoxin-OVA may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M PBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.1 It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 μM.2

HOE 689 (Ramnodigin) is a Digitoxin analog that demonstrates cytotoxic effects on lung cancer cells and induces apoptosis in NCI-H460 cancer cells, with an IC50 of 52 nM.

Gitoxin is a natural Na⁺/K⁺-ATPase inhibitor and metabolite of digitoxin, exhibiting antiarrhythmic activity with μM-level inhibition of human erythrocyte isoenzymes.

Thevebioside and digitoxin are cardiac glycosides, have cardiac action.