dbco-peg1

DBCO-PEG1, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG1-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG1-amine is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG1-NH-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG1-NHS ester is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for PROTAC molecule formation. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

DBCO-C-PEG1 is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, facilitating selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

DBCO-PEG10-DBCO is a PEG-based linker used in PROTACs, joining two essential ligands needed to form PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG12-acid is a PEG-based linker for PROTACs that connects two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

DBCO-PEG12-NHS ester is a PEG-based PROTAC linker for synthesising PROTAC molecules, whose DBCO group undergoes click chemistry with azide-containing molecules.

DBCO-PEG13-DBCO, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG13-NHS ester is a PEG-type PROTAC linker useful in the synthesis of PROTAC molecules. This compound acts as a click chemistry reagent and contains a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group.

Azido-PEG1 is a PEG-like PROTAC linker for the synthesis of PROTAC molecules.Azido-PEG1 contains an Azide moiety and can undergo click chemistry reaction CuAAc with molecules containing an Alkyne moiety or SPAAC with molecules containing a DBCO or BCN moiety.

Boc-PEG1-PPG2-C2-azido is a PROTAC linker of the PEG class, utilized in PROTAC molecule synthesis. This compound acts as a click chemistry reagent containing an azide group, enabling copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it participates in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.

Lenalidomide 4'-PEG1-azide (Compound 4g) is an azide derivative of lenalidomide. This compound includes a cereblon ligand and a linker. It functions as a click chemistry reagent, featuring an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules containing alkyne groups, and also participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.