dbco-biotin

DBCO-Biotin (Azadibenzocyclooctyne-Biotin conjugate) is a PROTAC linker based on the alkyl chain.

DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into an azide-labelled biomolecule via a copper-free catalytic alkyl azide reaction (SPAAC). azide-labelled biomolecules via a copper-free catalytic alkyl azide reaction (SPAAC).

DBCO-S-S-PEG3-biotin is a cleavable reagent for the introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved with reducing agents such as DTT, BME, and TCEP to remove the biotin label. PEG linkers can also be used in the synthesis of PROTACs.

DBCO-Sulfo-Link-biotin is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Dde Biotin-PEG4-DBCO is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG12-biotin is a PEG-based linker for PROTACs that connects two essential ligands critical for forming PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG2-Biotin is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG6-Biotin is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the creation of PROTAC molecules. This linker promotes selective protein degradation by utilizing the ubiquitin-proteasome system [within cells].

DBCO-SS-PEG4-Biotin, a cleavable, mid-functional ADC linker with a 4-unit PEG moiety, is used in the synthesis of antibody-drug conjugates (ADCs)[1].

Diazo Biotin-PEG3-DBCO is a cleavable, three-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker suitable for synthesizing PROTACs [1].

PC DBCO-PEG3-biotin is a trimeric polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis, incorporating a cleavable moiety with a dibenzocyclooctyne (DBCO) group and a biotin molecule, enabling efficient drug attachment to antibodies for targeted delivery and controlled release of therapeutic agents in ADCs[1].

WSPC Biotin-PEG3-DBCO is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the assembly of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Biotin-PEG-azide (MW 600) is a PEG-based PROTAC linker suitable for synthesizing PROTACs. It features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can undergo strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Biotin-PEG-azide (MW 5000) is a PROTAC linker based on a PEG structure, utilized in the preparation of PROTACs. It contains an azide group that can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC) with molecules that have alkyne groups. Additionally, it can participate in a strain-promoted azide-alkyne cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

Biotin-PEG4-SS-azide, a biotin-labeled ADC linker, is primarily utilized in the synthesis of antibody-drug conjugates (ADCs). This compound serves as a click chemistry reagent featuring an Azide group, enabling it to partake in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-bearing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

DBCO-PEG-Biotin (MW 2000) is a clickable biotinylation compound that enables copper-free click chemistry with azide molecules, resulting in the formation of stable triazole bonds.

DBCO-PEG-Biotin (MW 20000) is a click chemistry biotin conjugate that reacts with azide molecules through copper-free click chemistry, resulting in the formation of stable triazole bonds.

DBCO-PEG-Biotin (MW 1000) is a click chemistry biotinylated compound that can react with azide molecules through copper-free click chemistry to form a stable triazole linkage.

DBCO-PEG-Biotin (MW 10000) is a click chemistry biotinylated compound that can react with azide molecules through copper-free click chemistry to form stable triazole bonds.

DBCO-PEG-Biotin (MW 40000) is a click chemistry biotin derivative that can undergo copper-free click chemistry with azide molecules to form stable triazole bonds.

DBCO-PEG-Biotin (MW 5000) is a click chemistry biotinylation reagent that can perform copper-free cycloaddition with azide-containing molecules, resulting in a stable triazole bond.

DBCO-PEG-Biotin (MW 3400) is a clickable biotin compound that can undergo copper-free click chemistry with azide molecules, resulting in the formation of a stable triazole linkage.

Azide-PEG2-Desthiobiotin is a PEG derivative composed of desthiobiotin, two PEG units, and an azide group (azide). Biotin forms a stable non-covalent bond with streptavidin (Streptavidin). The azide group can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.