d-mannitol

D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. D-Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.

1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial compound effective against various Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Its application potential lies in its ability to combat common antibiotic-resistant bacterial infections effectively. 1-Amino-2,5-anhydro-1-deoxy-D-mannitol may emerge as a novel antimicrobial agent in clinical inhibition.

1,5-Dideoxy-1,5-imino-D-mannitol is an antibiotic with antibacterial properties.

2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver.. It is phosphorylated in the liver, which decreases available ATP and signals eating behavior in rats through a vagal nerve mechanism.

1,4:3,6-Dianhydro-D-mannitol (1,4:3,6-Dianhydromannitol) is a commonly used intermediate compound and a derivative of Isosorbide .Some derivatives of 1,4:3,6-Dianhydro-D-mannitol exhibit potent inhibitory activity against KLK5 and KLK7.This compound can be used in the study of HCV infection and KLK5/KLK7-related diseases.

1,5-Anhydro-D-mannitol, the inactive analog of 1,5-Anhydrosorbitol, serves as an experimental control, whereas 1,5-Anhydrosorbitol acts as a short-term glycemic control marker.

D-Mannitol-d4 (Mannitol-d4) is the deuterium-labeled variant of D-Mannitol. D-Mannitol (Mannitol) is a resistant sugar with oral activity, widely utilized in the food and pharmaceutical industries. It facilitates calcium and magnesium absorption and retention via cecal fermentation and reduces tissue edema as an osmotic diuretic. Additionally, D-Mannitol can enhance brown fat formation, improve insulin action, lower blood glucose levels, and promote the conversion of white adipose cells to brown via β3-adrenergic receptor (β3-AR), PGC1α, and PKA pathways. It is also used to maintain osmotic pressure between plant protoplasts and culture media, protecting cells when the cell wall is weakened or removed.

D-Mannitol (Standard) is the standard substance of D-Mannitol, suitable for quantitative analysis, quality control, and biochemical experiments, etc. D-Mannitol is a diuretic and a renal diagnostic auxiliary agent with weak renal vascular dilation activity.

D-Mannitol-1,1,2,3,4,5,6,6-[D8] (Standard) is a reference standard of D-Mannitol-1,1,2,3,4,5,6,6-[D8] intended for quantitative analysis, quality control, and related biochemical research applications.

Podoblastin A (D-mannitol) is a useful organic compound for research related to life sciences and the catalog number is TSP-41077145.

D-Mannitol 1,2:5,6-bis-acetonide is an intermediate.

2,3:5,6-Di-O-isopropylidene-D-mannitol is a biochemical reagent used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It encompasses carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely linked to fundamental research, biomedicine, and biotechnology.

2-Deoxy-1,3:4,5-di-O-isopropylidene-2-oxamoylamino-D-mannitol is a reagent used in biochemical reactions.

1,5-Anhydro-D-mannitol peracetate is a reagent used in biochemical reactions.

D-Mannitol, 2,5-anhydro, 1,3,4,6-tetraacetate is a biochemical reagent utilized in glycoscience research. Glycoscience examines the structure, synthesis, biology, and evolution of sugars, involving carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans within biological systems. This area is closely linked with fundamental research, biomedicine, and biotechnology.

3,4-O-Isopropylidene-D-mannitol is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

DL-Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake

Trimethylsilyl-D-(+)-mannitol is a compound that possesses osmoprotectant activity and can effectively remove reactive oxygen species (ROS), offering protection for plants and microorganisms.

3-Deoxy-3-fluoro-D-fructose (Compound 12) is a derivative of 2,5-Anhydro-D-mannitol. It serves as a selective probe for hexose transporter 5 (GLUT5). This compound inhibits the transport of [14C]-labeled D-fructose by GLUT5, with IC50 values of 1.16 µM in EMT-6 cells and 2.37 µM in MCF-7 cells. Additionally, 3-Deoxy-3-fluoro-D-fructose is useful for positron emission tomography (PET) imaging in cancer studies.

Dianhydromannitol, Dihyro- and tetrahydrofuran building blocks from 1,4:3,6-dianhydromannitol.

2,5-Anhydro-D-glucitol-1,6-diphosphate acts primarily as a moderate stimulant of yeast Pyruvate Kinase and serves as an analog to the a-form, 2,5-anhydro-D-mannitol 1,6-bisphosphate, which is a potent allosteric activator of Pyruvate Kinase [1].

DL-Mannitol (Standard) is the standard substance of DL-Mannitol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. DL-Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake