d-d α chain

Raffinose (Melitriose) is an indigestible short-chain oligosaccharide, a trisaccharide composed of galactose, glucose and fructose, found in many plants. It can be hydrolyzed by α-galactosidase (α-GAL) to D-galactose and sucrose.

H-D-Phe-Pip-Arg-pNA acetate is a chromogenic substrate whose sequence mimics the N-terminal region of thrombin's natural substrate fibrinogen α-chain. It is highly specific to thrombin and can be used for the activity detection of antithrombin Ⅲ heparin cofactor (AT-III). The AT-III detection method based on this chromogenic substrate features high sensitivity, accurate results and simple operation.