d-7 hydrochloride

Propafenone-D7 hydrochloride is the deuterium labeled Propafenone hydrochloride (T6955), and is a classic anti-arrhythmic medication.

4-Hydroxypropranolol-D7 hydrochloride is deuterium-labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochloride (T10150) is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).

Propranolol-D7 hydrochloride is a deuterated isotope marker of Propranolol hydrochloride (TMSM-1966), which can be used for isotope tracing. Propranolol is a non-selective beta-blocker used for hypertension research

(Rac)-Atomoxetine-D7 hydrochloride is a deuterium labeled  (Rac)-Atomoxetine hydrochloride (T68621). (Rac)-Atomoxetine hydrochloride is a racemic form of Atomoxetine hydrochloride.

Rotigotine-D7 hydrochloride is the deuterium labeled Rotigotine Hydrochloride (T21446). Rotigotine (N-0923) is an agonist of dopamine D2 and D3 receptor.

N-Desbutyl Dronedarone-D7 hydrochloride is the deuterium-labelled isomer of N-Desbutyl Dronedarone hydrochloride (T35712), used for isotope tracing. N-Desbutyl Dronedarone is a metabolite of the antiarrhythmic drug Dronedarone.

Isoproterenol-D7 hydrochloride Isoproterenol-D7 is intended for use as an internal standard for the quantification of isoproterenol by GC- or LC-MS. Isoproterenol is an agonist of β1- and β2-adrenergic receptors (β1- and β2-ARs; Kis = 224 and 458 nM, respectively). It is selective for β1- and β2-ARs over β3-ARs (Ki = 1,570 nM). Isoproterenol inhibits contractions in isolated field-stimulated rat vas deferens (EC50 = 45.6 nM). In vivo, isoproterenol (0.33 mg/kg) decreases blood pressure and increases water intake in nephrectomized rats. It reduces blood pressure and increases heart rate in renal hypertensive rabbits. Isoproterenol inhibits histamine-induced bronchospasms in anesthetized dogs. Formulations containing isoproterenol have been used in the treatment of bradydysrhythmias and to improve breathing during anesthesia.

ACT-281959, a prodrug of ACT-246475, is a novel potent and selective P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel. ACT-281959 showed antithrombotic efficacy after oral administration in the rat ferric chloride model. ACT-281959 entered clinical studies in healthy volunteers.

Esmolol-D7 hydrochloride is a deuterated compound of Esmolol Hydrochloride (TMSM-1120). Esmolol hydrochloride has a CAS number of 81161-17-3. Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension. Esmolol has not been linked to instances of clinically apparent drug induced liver injury.

L-Arginine-D7 hydrochloride is the deuterated form of L-Arginine hydrochloride. L-Arginine hydrochloride (T0670) ( (S)- (+)-Arginine hydrochloride) serves as a nitrogen donor in the synthesis of nitric oxide and acts as a vasodilator.

L-Arginine-13C6,15N4,D7 hydrochloride is an L-Arginine hydrochloride (T0670) compound labeled with 13C, 15N, and deuterium. This compound, known as L-Arginine hydrochloride (T0670) ( (S)- (+)-Arginine hydrochloride), serves as a nitrogen donor for nitric oxide synthesis and acts as a vasodilator.

Donepezil-D7 hydrochloride is a deuterated compound of Donepezil Hydrochloride (T6478).

Norverapamil-D7 hydrochloride is a 2H-labeled Norverapamil hydrochloride (TMSM-3613), a calcium channel blocker and P-glycoprotein (P-gp) inhibitor, used in cardiovascular and neurodegenerative disease research.

Oxprenolol-D7 hydrochloride is a deuterated compound of Oxprenolol hydrochloride. Oxprenolol hydrochloride (T19793) has a CAS number of 6452-73-9. Oxprenolol hydrochloride (T19793) is a non-selectiveβ-adrenergic blocking agent (Ki = 7.10 nM).

R-Verapamil-D7 hydrochloride is a deuterated compound of R-Verapamil hydrochloride (TMSM-6393). R-Verapamil hydrochloride has a CAS number of 1188265-55-5.

S-Verapamil-D7 hydrochloride is a deuterated compound of S-Verapamil hydrochloride (TMSM-6393). S-Verapamil hydrochloride has a CAS number of 1188265-55-5.

Metoprolol-D7 hydrochloride is a deuterated compound of Metoprolol Hydrochloride. Metoprolol Hydrochloride (T71800) has a CAS number of 56392-18-8. Metoprolol is a selective β1 receptor blocker medication. Metoprolol is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate.

Dapoxetine-D7 hydrochloride is a deuterated compound of Dapoxetine hydrochloride. Dapoxetine hydrochloride (T6461) has a CAS number of 129938-20-1. Dapoxetine hydrochloride is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.

Verapamil-D7 hydrochloride is a deuterated compound of Verapamil Hydrochloride. Verapamil Hydrochloride (T1010) has a CAS number of 152-11-4. Verapamil hydrochloride is a calcium channel blocker that is a class IV anti-arrhythmia agent.

4-Hydroxy propranolol-D7 hydrochloride is a deuterated compound of 4-Hydroxy propranolol hydrochloride (T10150). 4-Hydroxy propranolol hydrochloride has a CAS number of 14133-90-5. 4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).

Propranolol‑D7 hydrochloride (Standard) is a reference standard of Propranolol‑D7 Hydrochloride intended for quantitative analysis, quality control, and related biochemical research applications

Alvimopan Metabolite (Adl08-0011)-D7 hydrochloride Salt (Standard) is a reference standard of Alvimopan Metabolite (Adl08-0011)-[D7], Hydrochloride Salt intended for quantitative analysis, quality control, and related biochemical research applications.

L-Arginine-D7 Hydrochloride (Standard) is a reference standard of L-Arginine-D7 Hydrochloride intended for quantitative analysis, quality control, and related biochemical research applications. L-Arginine-d7(hydrochloride) is the deuterated form of L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) serves as a nitrogen donor in the synthesis of nitric oxide and acts as a vasodilator.

Verapamil-D7 Hydrochloride (Standard) is a reference standard of Verapamil-D7 Hydrochloride intended for quantitative analysis, quality control, and related biochemical research applications. Verapamil-d7 Hydrochloride is a deuterated compound of Verapamil Hydrochloride. Verapamil Hydrochloride has a CAS number of 152-11-4. Verapamil hydrochloride is a calcium channel blocker that is a class IV anti-arrhythmia agent.