clomipramine

Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of suicide in those over the age of 65. It is similar to Imipramine in that selective inhibition of the serotonin uptake in the brain.

Clomipramine-D3 hydrochloride is the deuterium-labeled Clomipramine hydrochloride (TMSM-0794). Clomipramine is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM).

N-Desmethyl Clomipramine hydrochloride is a primary plasma N-desmethyl Clomipramine metabolite .

N-Desmethyl Clomipramine-D3 is the deuterium labeled N-Desmethyl Clomipramine.

N-Desmethyl Clomipramine-D3 (Standard) is a reference standard of N-Desmethyl Clomipramine-D3 intended for quantitative analysis, quality control, and related biochemical research applications. N-Desmethyl Clomipramine-d is the deuterium labeled N-Desmethyl Clomipramine.

Clomipramine D3 Hydrochloride (Standard) is a reference standard of Clomipramine D3 Hydrochloride intended for quantitative analysis, quality control, and related biochemical research applications.

Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.

Clomipramine-D3 is the deuterium-labeled Clomipramine. Clomipramine (T21013) is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM).

Clomipramine Hydrochloride (Standard) is the standard substance of Clomipramine Hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.

N-Desmethyl Clomipramine HCl (Standard) is a reference standard for research and analysis in studies involving N-Desmethyl Clomipramine HCl. N-Desmethyl Clomipramine hydrochloride is a primary plasma N-desmethyl Clomipramine metabolite .

N-Desmethylclomipramine-[D7], Hydrochloride Salt (Standard) is a reference standard of N-Desmethylclomipramine-[D7], Hydrochloride Salt intended for quantitative analysis, quality control, and related biochemical research applications.

PIM-35, an indole derivative with properties similar to antidepressants, exhibits weaker norepinephrine uptake inhibition compared to standard compounds. Prolonged use of PIM-35 does not affect the quantity or affinity of alpha 2, beta 1-, and beta 2-adrenergic receptors. Additionally, PIM-35 influences the serotonin system, resembling antidepressant compounds like paroxetine and clomipramine.