ck-37

CK37 regulates the biological activity of Choline Kinase-α. CK37 is a small-molecule inhibitor primarily utilized for phosphorylation and dephosphorylation research applications. CK37 is relevant for studies involving phospholipid metabolism, kinase-associated signaling pathways, and membrane biosynthesis regulation.

Frenolicin is a selective inhibitor of Prx1 and Grx3 through covalent modification of active-site cysteines.

iHCK-37 (ASN05260065) is a selective Hck inhibitor with antitumor activity, blocking HIV-1 viral replication. iHCK-37 reduces PI3K/AKT and MAPK/ERK pathway activation after erythropoietin induction in high Hck-expressing cells, useful in chronic myelogenous leukemia (CML) research.

Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.