chloroquine phosphate

Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).

(R)-Hydroxychloroquine ((R)-HCQ) phosphate is an isomer of Hydroxychloroquine. It inhibits insulin-metabolizing enzymes in the cytosolic fraction of liver homogenates in both healthy and diabetic rats.

G6PD activator AG1 is a glucose-6-phosphate dehydrogenase (G6PD) agonist that promotes glucose-6-phosphate dehydrogenase (G6PD) oligomerization to a catalytically competent form. G6PD activator AG1 reduces oxidative stress in cells and zebrafish, reduces chloroquine or diamide-induced oxidative stress in human erythrocytes, and can be used to study glucose-6-phosphate dehydrogenase deficiency.

Chloroquine-D5 diphosphate is the deuterated form of Chloroquine (phosphate). This compound is widely utilized as an antimalarial and anti-inflammatory agent for malaria and rheumatoid arthritis. Additionally, Chloroquine phosphate functions as an inhibitor of autophagy and toll-like receptors (TLRs) and effectively inhibits SARS-CoV-2 (COVID-19) infection.