chemerin-9

Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, retaining most of the activity of the full protein. Chemerin-9 acts as a ChemR23/CMKLR1 agonist, preventing atherosclerosis whilst inhibiting NLRP3 inflammasome activation and promoting Aβ microglial clearance. It modulates blood pressure and sympathetic nervous system activity via glutamate receptor-mediated ROS production.

Chemerin-9 (149-157) acetate, The nonapeptide 149,YFPGQFAFS157 (chemerin-9), corresponding to the C terminus of processed chemerin, retained most of the activity of the full-size protein, with regard to agonism toward the chemerinR.the natural ligand of C

Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM). Corresponds to C-terminal of full length mouse Chemerin, amino acids 148 - 156.

The nonapeptide 149,YFPGQFAFS157 (chemerin-9), corresponding to the C terminus of processed chemerin, retained most of the activity of the full-size protein, with regard to agonism toward the chemerinR.the natural ligand of ChemR23 (chemerinR).