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cdk-8-in-1

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
CDK8-IN-1
T107401629633-48-2In house
CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).
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6-8 weeks
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CDK8/19-IN-1
T107391818427-07-4
CDK8 19-IN-1 is a selective, orally bioavailable dual inhibitor of CDK8 and CDK19, with IC50 values of 0.46 nM for CDK8, 0.99 nM for CDK19, and 270 nM for [CDK9].
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6-8 weeks
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CDK2-IN-18
T86027364735-73-9
CDK2-IN-18 (compound 8q) serves as a powerful inhibitor of CDK 2 E and CDK 4 D1, showing IC50 values of 8 nM and 46 nM, respectively. It effectively inhibits tumor cell proliferation [1].
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10-14 weeks
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