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  • Bcr-Abl
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breakpoint

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  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
    3
    TargetMol | Recombinant_Protein
Olverembatinib
GZD 824
T30711257628-77-5
Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).
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TargetMol | Citations Cited
Olverembatinib dimesylate
HQP1351, GZD824 Dimesylate
T24291421783-64-3
Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).
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BCR-ABL-IN-5
T633321795736-60-5
BCR-ABL-IN-5 is a Bcr-Abl (Breakpoint cluster region-Abelson) kinase inhibitor that acts on Bcr-AblWT (IC50: 0.014 μM) and Bcr-AblT3151 (IC50: 0.45 μM) and exhibits some anti-proliferative effects on leukemic cells. effect.
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6-8 weeks
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Anti-hepatic fibrosis agent 2
T830642380421-60-1
Compound 6k, also known as Anti-hepatic fibrosis agent 2, is an orally active inhibitor of the COL1A1 enzyme and exerts anti-fibrogenic effects by targeting the Ewing sarcoma breakpoint region 1 (EWSR1)[1].
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8-10 weeks
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