biotin-peg-amine

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Biotin-PEG-amine (MW 3400) is a polyethylene glycol (PEG)-based linker compound used in the synthesis of PROTACs [1].

Biotin-PEG-Amine (MW 10000) (Biotin-PEG-NH2 (MW 10000)) is a biotinylated PEG polymer that includes a free amine group (-NH2). This amine group can form an amide bond by reacting with activated NHS esters. Compounds labeled with biotin can be linked to avidin or streptavidin for further purification or detection.

Biotin-PEG-Amine (MW 5000) (Biotin-PEG-NH2 (MW 5000)) is a biotin PEG polymer featuring a free amine group (-NH2). This amine group can react by forming an amide bond with activated NHS esters. Biotin-labeled compounds can bind to avidin or streptavidin for subsequent purification or detection.

Biotin-PEG-Amine (MW 20000) (Biotin-PEG-NH2 (MW 20000)) is a biotin PEG polymer that contains a free amine group (-NH2). This amine group can react with activated NHS esters to form an amide bond. Biotin-labeled compounds can bind with avidin or streptavidin for further purification or detection.

Biotin-PEG-Amine (MW 40000) (Biotin-PEG-NH2 (MW 40000)) is a biotinylated PEG polymer that contains a free amine group (-NH2). This amine group can react with activated NHS esters to form an amide bond. The biotin-labeled compound can bind to avidin or streptavidin for further purification or detection.

Biotin-PEG11-amine is a PEG-based linker with biotin labeling which finds application in the synthesis of PROTACs[1].

Biotin-PEG4-amine is a biotinylated PEGylated amine linker that provides a flexible spacer suitable for PROTAC synthesis and bioconjugation workflows. Biotin-PEG4-amine facilitates efficient ligand attachment to proteins or small molecules via its terminal amine while preserving accessibility for streptavidin-based detection or enrichment techniques.

Biotin-PEG5-amine is a PEG-based PROTAC linker labeled with biotin. It is utilized in the synthesis of PROTACs, a class of molecules with the ability to target and degrade specific proteins[1].

Biotin-C1-PEG3-C3-amine (TFA) is a polyethylene glycol (PEG) linker essential for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Biotin-PEG23-amine is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Biotin-PEG6-amine is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG8-amine is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

Biotin-PEG7-amine is a PEG derivative containing a biotin group and a terminal primary amine group. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound.

Biotin-PEG10-amine is a PROTAC linker belonging to the PEG category, used for the synthesis of PROTAC molecules.

Biotin-PEG-amine (MW 3400) is a PROTAC linker belonging to the PEG category and can be utilized in the synthesis of PROTAC molecules.

Biotin-PEG9-amine is a PROTAC linker belonging to the PEG class, utilized in the synthesis of PROTAC molecules.

Biotin-PEG32-NHS ester is a PEG derivative composed of Biotin, 32 PEG units, and an NHS ester. Biotin forms a stable non-covalent interaction with streptavidin (Streptavidin). The NHS ester reacts with amino acids or other amine-containing molecules.

Amine-PEG1-Desthiobiotin is a PEG derivative composed of desthiobiotin, a single PEG unit, and an amine group (Amine). Desthiobiotin acts as a biotin analog with a reversible and weaker affinity for streptavidin or avidin. The amine group can react with other chemical groups (such as carboxyl or aldehyde) to form stable bonds.

NHS-PEG4-biotinidase resistant biotin is a biotinylation reagent featuring a terminal NHS ester. The hydrophilic PEG spacer enhances its solubility in aqueous media. NHS ester is suitable for labeling primary amines (-NH2) found in proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Biotinyl-8-amino-3,6-dioxaoctanoic acid is a biotinylation reagent linked to a PEG chain, enhancing water solubility. Biotin acts as an affinity ligand suitable for biochemical applications such as pull-down assays or binding with streptavidin proteins. The carboxyl group can react with amine-containing molecules in the presence of activators like HATU.

Mal-Cyclohexyl-PEG3-Biotin is a PEG linker that includes a maleimide moiety and a biotin group. The maleimide specifically reacts with thiols at a pH between 6.5 and 7.5, forming a stable thioether bond. Biotinylation can occur with amine molecules in the presence of activators like EDC or HATU. The PEG linkage, attached to biotin, creates an extended spacer arm, facilitating biotin's access to protein binding sites. Additionally, the PEG component enhances the solubility of the biotin-PEG conjugate significantly.

N-Boc-Biocytin is a biotin PEG linker that incorporates both a carboxyl group and a Boc-protected amine. The carboxyl group reacts with a primary amine (-NH2) to form a stable, irreversible amide bond. The Boc group can be removed under acidic conditions to yield a free amine suitable for further conjugation.