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(6)
By Target- Epigenetic Reader Domain
- PROTACs(2)
- Apoptosis(1)
- HIV Protease(1)
- Ligands for Target Protein for PROTAC(1)
- Others(2)
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Results for "
bet brd
" in TargetMol Product Catalog- Inhibitors & Agonists9
- PROTAC Products4
- Recombinant Protein1
PROTAC BRD4 ligand-1
T125512313230-51-0In house
PROTAC BRD4 ligand-1, a component of Protac GNE-987, is a ligand for BRD4 and acts as an inhibitor of BET.
- $125
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SNIPER(BRD)-1
T169052095244-54-3
SNIPER(BRD)-1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+)-JQ-1, linked together. It promotes the degradation of BRD4 through the ubiquitin-proteasome pathway and effectively degrades cIAP1, cIAP2, and XIAP with IC50 values of 6.8 nM, 17 nM, and 49nM, respectively[1].
- Inquiry Price
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BTR2004
T207008
BTR2004 is a selective PROTAC degrader targeting the BET family (BRD2/3/4) proteins. It facilitates the formation of a ternary complex with BRD proteins and KLHL20, leading to ubiquitination and proteasomal degradation via the UPS pathway. BTR2004 shows potential for research in PC3 prostate cancer and MDA-MB-231 breast cancer cell lines.
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