benzophenone 8

Dioxybenzone (Benzophenone-8) is an organic agent that blocks UVB and short-wave UVA ultraviolet radiation.

Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 μM) and suppressing the proliferation of T cells. Oral administration of isogarcinol in mice decreases delayed type hypersensitivity, prolongs graft survival in allogeneic skin transplants, suppresses inflammation in collagen-induced arthritis, and reduces clinical symptoms in experimental autoimmune encephalomyelitis. Isogarcinol inhibits the proliferation of HL-60 and PC-3 cancer cells (IC50s = 4 and 8 μg/ml, respectively) through cell cycle arrest and apoptosis.

Dioxybenzone (Standard) is the standard substance of Dioxybenzone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Dioxybenzone (Benzophenone-8) is an organic agent that blocks UVB and short-wave UVA ultraviolet radiation.