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By Tag By Expression System- E. coli(2)
By Species- Human(2)
By SPR-compatible Buffer- Buffer exchange required(2)
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Results for "
bcl-w
" in TargetMol Product Catalog- Inhibitors & Agonists15
- Peptide Products2
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- Recombinant Protein2
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ComparePPP1R51, BCL-W, BCLW, BCL2-like 2, BCL2-L-2
TMPY-02004
Expression system: E. coli
Length: 1-172, Partial
Activity: Not Tested
Length: 1-172, Partial
Activity: Not Tested
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CompareKIAA0271, BCLW, Bcl-2-Like Protein 2, Bcl2-L-2, BCL2L2, Apoptosis Regulator Bcl-W
TMPJ-00584
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
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