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autophagosome-tethering compounds

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LC3-mHTT-IN-AN2
5,7-Dihydroxy-4-phenylcoumarin
T50707758-73-8
LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.
  • $41
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LC3-mHTT-IN-AN1
T8081486443-73-6
LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
  • $35
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