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Results for "

autoimmunity inhibitor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    10
    TargetMol | Inhibitors_Agonists
JAK2/STAT3-IN-1
T727542485758-50-5In house
JAK2 STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.
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6-8 weeks
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enpatoran
T95702101938-42-3In house
Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM). Enpatoran was found to be inactive against TLR3, TLR4, and TLR9 in vitro and in vivo.
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Azathioprine
BW 57-322
T1237446-86-6
Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.
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RVX-297
RVX297
T286281044871-04-6
RVX-297 is a BD2 selective inhibitor of BET bromodomains. RVX-297 preferentially binds to the BD2 domains of the BET bromodomain and Extra Terminal (BET) family of protein.
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TargetMol | Inhibitor Sale
HG-12-6
T115592222354-57-4
HG-12-6 is a type II inhibitor of IRAK4, demonstrating preferential binding to unphosphorylated inactive IRAK4 (IC50: 165 nM) and modulating IRAK4 activity in autoimmunity and inflammation.
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3-6 months
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LTV-1
T11889347379-29-7
LTV-1 has the potential for autoimmunity treatment. LTV-1 is a potent lymphoid tyrosine phosphatase (LYP) inhibitor in T cells with an IC50 of 508 nM.
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6-8 weeks
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Syk-IN-4
T37077
Syk-IN-4 is a potent, selective, and orally bioavailable inhibitor of SYK, with an IC50 of 0.31 nM, targeting SYK, a potential therapeutic target for autoimmunity and hematological cancers[1].
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ido2-in-1
T638142803768-09-2
IDO2-IN-1 is a potent, orally active indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor, exhibiting an IC50 value of 112 nM. It is applicable in research related to inflammatory autoimmunity [1].
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10-14 weeks
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P2X7-IN-2
T733351058709-63-9
P2X7-IN-2, a P2X7 receptor inhibitor, effectively suppresses IL-Iβ release, demonstrating an inhibitory concentration (IC50) value of 0.01 nM. This compound is utilized in the study of autoimmunity, inflammation, and cardiovascular disease.
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6-8 weeks
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P2X7-IN-2 TFA
T75254
P2X7-IN-2 TFA (compound 58) is a P2X7 receptor inhibitor with an IC50 value of 0.01 nM for inhibiting IL-Iβ release, used in research on autoimmunity, inflammation, and cardiovascular disease [1].
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