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Results for "

apixaban

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    6
    TargetMol | Inhibitors_Agonists
  • Isotope Products
    1
    TargetMol | Isotope_Products
Apixaban
BMS-562247-01
T1736503612-47-3
Apixaban (BMS-562247-01) is an orally active anticoagulant that inhibits coagulation factor Xa, directly preventing the conversion of prothrombin to thrombin and the formation of cross-linked fibrin clots.
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Apixaban 13C,d3
BMS-562247-01 13CD3, BMS-56224701 13CD3, Apixaban 13CD3
T103491261393-15-0
Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor Xa and is used in thromboembolism studies
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7-10 days
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O-Desmethyl apixaban
T12279503612-76-8
O-Desmethyl apixaban is a metabolite of Apixaban and a highly selective, reversible inhibitor of Factor Xa, with Ki values of 0.08 nM in humans and 0.17 nM in rabbits.
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3-6 months
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O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium (503612-76-8 free base)
T19488
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.
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3-6 months
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O-Demethyl apixaban sulfate
T714291118765-14-2
O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases.
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8-10 weeks
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Adagrasib
MRTX849
T83692326521-71-3
Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib exhibits inhibitory activity against KRAS G12C mutant tumors.
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TargetMol | Inhibitor Hot