antipyretic compound

Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.

Butibufen (FF-106) is an orally active non-steroidal anti-inflammatory compound, a potential cyclooxygenase inhibitor with analgesic and antipyretic activity, and inhibits urea synthesis.Butibufen has been used in the study of rheumatic diseases.

Isoxepac (Olopatadine USP Related Compound C) is a non-steroidal anti-antiphlogistic agent and analgesic.

Etoricoxib-d4 is a deuterated form of Etoricoxib. Etoricoxib is a synthetic non-steroidal anti-inflammatory compound, an orally available and selective COX-2 inhibitor with antipyretic, analgesic, and potential anticancer properties.

Detanosal is a compound that possesses antipyretic (fever-reducing), analgesic (pain-relieving), and anti-inflammatory effects.

AGU654 (Compound 44) is a selective mPGES-1 inhibitor with an IC50 value of 2.9 nM against mPGES-1. By inhibiting mPGES-1, AGU654 interrupts the pathway where COX-1/2 converts arachidonic acid to prostaglandin E2 (PGE2), effectively reducing inflammatory responses, pain, and fever symptoms. In models using activated human monocyte-derived macrophages and whole blood, AGU654 selectively inhibits PGE2 production induced by bacterial endotoxins, while preserving the production of other prostaglandins. In guinea pig models, AGU654 significantly alleviates fever, inflammation, and inflammatory pain, demonstrating excellent anti-inflammatory, analgesic, and antipyretic effects. AGU654 holds promise as a new approach for researching inflammatory diseases and pain.

4-Desmethyl-2-methyl celecoxib (Compound 1g) is an orally active and selective cyclooxygenase-2 (COX-2) inhibitor, with an IC50 value of 0.069 μM. It possesses anti-inflammatory, analgesic, and antipyretic properties and can reduce prostaglandin synthesis. This compound is a promising candidate for research into inflammatory diseases and pain-related conditions, such as rheumatoid arthritis and osteoarthritis.

Oxametacin is a anti-inflammatory compound with analgesic, antipyretic and anti-inflammatory properties.

Acetaminophen Glucuronide sodium salt (APAP-glu) is a compound with antipyretic and analgesic activity and is an acetaminophen metabolite with potential nephrotoxicity.

Falimint is a compound with antipyretic and analgesic activity [1].

Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) known for its potent inhibition of prostaglandin-synthetase, exhibiting significant anti-inflammatory and antipyretic properties [1] [2].

Antipyrine-d3 is a deuterated compound of Antipyrine. Antipyrine has a CAS number of 60-80-0. Antipyrine, an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.

MAA-d3 is a deuterated compound of MAA. MAA has a CAS number of 519-98-2. 4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak anti-inflammatory properties.

MefenaMic Acid-d4 is a deuterated compound of MefenaMic Acid. MefenaMic Acid has a CAS number of 61-68-7. Mefenamic acid is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.

Flunixin-d3 (methyl-d3) is a deuterated compound of Flunixin. Flunixin has a CAS number of 38677-85-9. Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), antipyretic, and analgesic used in pigs, horses, and cattle.

Ibuprofen-d2 is a deuterated compound of Ibuprofen. Ibuprofen has a CAS number of 15687-27-1. Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.

Cinnamaldehyde (Standard) is the reference compound for quantitative analysis, quality control, and biochemical research. Cinnamaldehyde exhibits antipyretic and sedative activities, inhibits the invasive potential of MDA-MB-435S cancer cells through downregulation of miR-27a, induces reactive oxygen species, exerts vasodilatory and anticancer effects, and has potential as an adjuvant in combination therapy with chemotherapeutics such as 5-fluorouracil and oxaliplatin, while also inhibiting melanoma progression via suppression of VEGF and HIF-a-mediated angiogenesis.