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Results for "

akt i 1

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    5
    TargetMol | Inhibitors_Agonists
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    TargetMol | Natural_Products
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    TargetMol | Recombinant_Protein
akt-i-1
T25017473382-39-7
AKT-I-1 is a selective and reversible inhibitor of Akt1.
  • $140
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Polyphyllin I
T389550773-41-6
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.
  • $52
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TargetMol | Inhibitor Hot
Artemitin
Artemetin, Artemisetin, Erianthin
TCS1704479-90-3
1. Artemitin (Erianthin) has anti-inflammatory activity. 2. Artemitin (Erianthin) protects endothelial function by acting as antioxidant and antiapoptotic agent and through the activation of ERK1 2 and Akt. 3. Intravenous injection of Artemitin (Erianthin)(.75 mg kg) significantly reduces the hypertensive response to angiotensin I while increases the average length of bradykinin-induced hypotension.
  • $35
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AMG 511
T142141253573-53-3
AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks (Kis of 4 nM, 6 nM, 2 nM, and 1 nM for PI3Kα, β, δ, and γ, respectively), exhibiting anti-tumor activity in a mouse glioblastoma xenograft model[1]. AMG 511 significantly suppresses PI3K signaling as indicated by a decrease in p-Akt (Ser473).
  • $84
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TargetMol | Inhibitor Sale
Eutypenes I
TN8927
Eutypenes I (Compound 9) inhibits the secretion of VEGF-A, hampers the activation of VEGFR, and disrupts its downstream Erk Akt signaling pathway. It also suppresses the migration of HMEC-1 cells and demonstrates anti-angiogenic activity in a Sprague-Dawley rat model.
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