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a-64077

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
Zileuton
Abbott 64077, A 64077
T0477111406-87-2
Zileuton (A 64077) is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma.
  • $30
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TargetMol | Citations Cited
Zileuton sodium
Abbott 64077 sodium, A 64077 sodium
T21836118569-21-4
Zileuton sodium is a selective and reversible 5-lipoxygenase (5-LOX) inhibitor that suppresses LTB4 synthesis. It significantly reduces arachidonic acid-induced ear edema in mice (ED50 = 31 mg/kg) and is suitable for inflammation research.
  • $98
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