a 1226

A1-226 is a cephalosporin of the class of β-lactam antibiotics, it is originally derived from the fungus Acremonium.

ZW-1226 is a selective MRP1 inhibitor that reduces the uptake activity of MRP1 vesicles by 65% at a concentration of 5 μM. It inhibits MRP1 in a GSH-dependent manner and exhibits considerable selectivity towards MRP1 over other primary ABC transport proteins (including P-gp, BCRP, MRP2, and MRP3).

Anti-Mouse TIM-2 Antibody (RMT2-29) is a rat-derived Ig2a, λ antibody inhibitor targeting mouse TIM-2.

Mal-C2-amide-C10-tri-GalNAc (Compound 1226) serves as a binding ligand fragment for the asialoglycoprotein receptor (ASGPR) and constitutes part of lysosome-targeting bifunctional molecules. It facilitates the sequestration and degradation of extracellular target molecules within lysosomes and is applicable in autoimmune disease research.