T6401

Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. Azithromycin is commonly used in studies of bacterial infections.

ABN401 is a potent, selective, ATP-competitive inhibitor of c-MET (IC50: 10 nM). ABN401 exhibits cytotoxicity against MET-loving cancer cells. c-MET phosphorylation in tumour tissues is inhibited by ABN401. ABN401 can be used in anti-cancer studies.

GSK1820795A is a selective G2A/GPR132a antagonist and a telmisartan analog. GSK1820795A also exhibits angiotensin II receptor antagonist activity and partial PPARγ agonist activity. GSK1820795A effectively blocks the activating effects of N-acylamides on yeast cells expressing hGPR132a.

DNA gyrase B-IN-1 is a potent inhibitor of DNA gyrase B, exhibiting good binding affinity and stability. DNA gyrase B-IN-1 inhibits P. aeruginosa/i> DNA gyrase B (IC50: 2.2 μM).

RPT193 is an orally active CCR4 inhibitor that exhibits an inhibitory effect on the recruitment of Th2 inflammatory immune cells to inflammatory tissues and plays an important role in diseases such as atopic dermatitis, asthma and allergic inflammation.

Antitumor agent-58 is an antitumour agent that effectively inhibits colony formation and cell migration in MGC-803 cells and induces mitochondrial dysfunction in MGC-803 cells. Antitumor agent-58 exhibited potent inhibitory activity against tumour growth in xenograft models carrying MGC-803 cells.

FGFR4-IN-6 is a covalent, reversible FGFR4 inhibitor (IC50: 5.4 nM) that exhibits good oral pharmacokinetic properties. In a xenograft mouse model of the Hep3B2.1-7 HCC cell line, FGFR4-IN-6 was able to significantly induce tumour regression without significant toxicity.

WS-898 is a potent inhibitor of ABCB1 that reverses resistance to paclitaxel (PTX) in drug-resistant SW620/Ad300, KB-C2 and HEK293/ABCB1 cells with IC50 values of 5.0, 3.67 and 3.68 nM, respectively.

RORγt agonist 3 is a potent agonist of RORγt that induces Th17 cell differentiation, increases levels of pro-inflammatory cytokines, and enhances lymphocyte cytotoxicity. Moreover, [it] blocks the production of regulatory T cells and suppresses the immune response.

Anti-inflammatory agent 23 is an anti-inflammatory agent that inhibits LPS-activated NO production (IC50: 0.449 μM). anti-inflammatory agent 23 exhibits good affinity for p65 protein.

ZM514 is a potent inhibitor of CD73, acting on hCD73 (IC50: 1.39 μM) and mCD73 (IC50: 14.65 μM). zM514 has low cytotoxicity and can be used in anti-cancer studies.

Azithromycin-D3 is the deuterated form of Azithromycin. Azithromycin (T6401) (CP-62993) is a macrolide antibiotic frequently utilized in bacterial infection research.

Azithromycin-13C,D3 is the deuterated form of Azithromycin (T6401) labeled with 13C.

Azithromycin-13C-D3 the 13C and deuterated compound of Azithromycin. Azithromycin has a CAS number of 83905-01-5. Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.