T2817

Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.

Nifeviroc (TD-0232) is an orally active CCR5 antagonist used in the study of HIV-1 infection.

Nizofenone, a thromboxane A2 (TXA2) biosynthesis inhibitor, is used as a neuroprotective drug and used to treat stroke.

NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.