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Cat No. | Product Name | Synonyms | Targets |
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T2225 | 4-Hydroxyantipyrine | COX | |
4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine. | |||
T35337L | Teduglutide acetate | Glucagon Receptor | |
Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy. Teduglutide acetate partially restores small intestinal epithelial function through an altered distribution of claudin-10, facilitati... | |||
T9897 | 7-Methoxy-1-naphthaleneacetic acid | Others | |
7-Methoxy-1-naphthaleneacetic acid is an inhibitor of auxin action in plants. 7-Methoxy-1-naphthaleneacetic acid inhibits polar auxin transport and tropic responses associated with asymmetric auxin distribution in Arabid... | |||
T14835 | BTRX-335140 | CYM-53093 | Opioid Receptor |
BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. BTRX-335140... | |||
T13247 | UK-101 | UK101,UK 101 | Proteasome |
UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM. UK-101 has a 144-fold and 10-fold higher affinity for β1i ... | |||
T1083L | Theophylline monohydrate | Quibron | HDAC , PDE , Adenosine Receptor |
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ... | |||
T34166 | PROTAC_ERRalpha | ||
PROTAC_ERRalpha is a proteolysis targeting chimeras (PROTAC) which provides broad tissue distribution and knockdown of the targeted ERRalpha protein in tumor xenografts. | |||
T33392 | MIP-1095 I-123 | 123-I-MIP-1095,(123I)MIP 1095 | |
MIP-1095 I-123, as a radiotracer, is under investigation in clinical trial NCT00712829 (Evaluating the Safety, Pharmacokinetics, Tissue Distribution, Metabolism and Dosimetry of Two Prostate Cancer Imaging Agents). | |||
T24924 | Umibecestat HCl (1387560-01-1 free base) | CNP 520,Umibecestat HCl,Umibecestat hydrochloride,CNP520,CNP-520 | |
Umibecestat is a beta-secretase inhibitor. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies. | |||
T32082 | Histidyl-aspartyl-glutamyl-leucine | His-asp-glu-leu,Hdel sequence | |
HDEL intracellular distribution is characteristic of plant endoplasmic reticulum (ER). | |||
T26230 | Stilbamidine dihydrochloride | NSC 35605,NCI 174 | |
Stilbamidine dihydrochloride is a blocker of neuromuscular transmission and axonal conduction used to study the distribution of the drug in the organs and tissues of rats following intravenous injection. | |||
T82238 | HAPSBC | ||
HAPSBC, an S-benzyl iron chelator, modulates the intracellular distribution of ^59Fe [1]. | |||
T14289 | Anguizole | Others | |
Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B. It demonstrates its potency with an IC50 value, highlighting its specific target ac... | |||
T16993 | Taribavirin | Others | |
Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cel... | |||
T29154 | WB403 | WB-403,WB 403 | |
WB403 is a TGR5 activator. WB403 significantly decreases fasting blood glucose, postprandial blood glucose and HbA1c, improves glucose tolerance in type 2 diabetic mice. WB403 increases pancreatic β-cells and restores th... | |||
T13862L | Recilisib sodium | Brand name: Ex-RAD,ON 01210.Na,ON01210,ON-01210 | |
Recilisib, also known as ON 01210.Na, is a radioprotectant, which modifys cell cycle distribution patterns in cancer cells subjected to radiation therapy, and it has been identified as a potential candidate for radiation... | |||
T37290 | Resolvin D3 methyl ester | ||
Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cle... | |||
T16992 | Taribavirin hydrochloride | Others | |
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin hydrochloride is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distr... | |||
T30118 | Arbaclofen placarbil | XP 19986,XP19986,XP-19986 | |
Arbaclofen placarbil( XP19986) is a GABA(B) receptor agonist.Arbaclofen Placarbil is a novel R-baclofen prodrug with improved absorption, distribution, metabolism, and elimination properties compared to R-baclofen. And i... | |||
TP1529 | Galanin (1-19), human | ||
Galanin (1-19), human, represents the fragment encompassing amino acids 1 to 19 of the human galanin neuropeptide. Galanin (GAL) is known for its extensive distribution and multifaceted biological roles, such as regulati... | |||
T75381 | Bodipy TMR-X muscimol | ||
Bodipy TMR-X muscimol, a Bodipy-labeled muscimol (Ex=543 nm, Em=572 nm), acts as a GABAA agonist. This compound is utilized for visualizing the distribution of reversible brain inactivations [1]. | |||
T76369 | CEDAEVFKDSMVPGEK | ||
CEDAEVFKDSMVPGEK, the peptide sequence corresponding to the rat vanilloid receptor subtype 1 (VR1), facilitates the detection and mapping of VR1 distribution [1]. | |||
T75355 | LtIA-F | ||
LtIA-F, a novel fluorescent analogue of LtIA, offers extensive pharmacological tools for investigating the structure-function relationship, distribution, and ligand-binding domain of the α3β2 nAChR subtype. | |||
T69664 | Umibecestat HCl | ||
Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD... | |||
T35448 | 10-Thiastearic Acid | ||
Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools. 10-Thiastearic acid inhibits desaturation o... | |||
T37463 | CAY10704 | ||
CAY10704 is a potent inhibitor of hepatitis C virus (HCV) infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 μM). It displays good pharmacokinetics in m... | |||
T76395 | (Met(O)35)-Amyloid β-Protein (1-42) | ||
(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of Aβ40. This compound is utilized in Alzheimer’s disease (AD) re... | |||
T37169 | Resolvin D2 methyl ester | ||
Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. It evokes diverse anti-inflammatory effects which may mediate the resolution of infla... | |||
T37168 | Resolvin D1 methyl ester | Resolvin D1 methyl ester | |
Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in a... | |||
T72982 | DPNB-ABT594 | ||
DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates nAChRs containing α4β2 subunits over the α7 subunit. It is utilized to map the distribution of nAChRs on medial habenula (MHb) neurons, thereby facilitating ... | |||
T79438 | C-Myc inhibitor 11 | c-Myc | |
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat pharmacokinetic assays, making it suitable for cancer researc... | |||
T37586 | DMHAPC-Chol | ||
DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B... | |||
T73610 | Lipoprotein lipase | ||
Lipoprotein lipase, a multifunctional enzyme present in adipose tissue, heart, skeletal muscle, islets, and macrophages, plays a crucial role in normal lipoprotein metabolism, and the distribution and utilization of tiss... | |||
T81249 | Ru3 | PARP | |
Ru3 is a poly(ADP-ribose) polymerase 1 (PARP1) inhibitor that prompts apoptosis in MCF-7 cells through various mechanisms, including DNA damage induction, inhibition of DNA repair, alteration of cell cycle distribution, ... | |||
T82937 | ATV041 | ||
ATV041, an orally active compound that combines features of Ibuprofen and nucleotide analogues, enhances the oral pharmacokinetic (PK) profile and tissue distribution, exhibiting anti-mouse hepatitis virus (MHV) activity... | |||
T77254 | Maltodextrin, dextrose equivalent 16.5-19.5 | ||
Maltodextrin (dextrose equivalent 16.5-19.5) serves as an excipient in pharmaceutical applications. Excipients, also known as pharmaceutical auxiliaries, are chemical substances utilized in drug formulation alongside act... | |||
T37953 | Sphingomyelins (buttermilk) | ||
Sphingomyelins (SMs) are bioactive sphingolipids found in mammalian cell membranes.1SMs make up 2-15% of the total organ phospholipid population but are found at higher concentrations in the brain and myelin sheaths surr... | |||
T68765 | Spirorenone | ||
Spirorenone is an androstadienone derivative as a highly effective aldosterone antagonist. Spirorenone is 8.6 times as potent as spironolactone, but showed a lower affinity for the mineralocorticoid receptors. In phase I... | |||
T70914 | GBR-12935 maleate | ||
GBR-12935 is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labe... | |||
T68356 | AM-3189 | ||
AM-3189 is a potent and selective GPR40 Agonist with minimal CNS penetration, superior pharmacokinetic properties and in vivo efficacy comparable to AMG 837. AM-3189 maintains the in vivo efficacy of AMG 837 while displa... | |||
T75329 | Cellulose | ||
Cellulose can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical... | |||
T77228 | Polyoxyethylene Sorbitan Monostearate | ||
Polyoxyethylene Sorbitan Monostearate, an ester derived from the saturated fatty acid stearic acid (C18:0), serves multiple roles in pharmaceutical formulations, including as a surfactant, emulsifier, solubilizer, and we... | |||
T76180 | Urocortin III (human) | ||
Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide that primarily interacts with and activates the CRF receptor type 2 (CRF-R2), showing a specific distribution in the central nervous system ... | |||
T71252 | PC-046 | ||
PC-046 is a potent tubulin-binding agent, which was originally identified for development based on selective activity in deleted in pancreas cancer locus 4 (DPC4/SMAD4) deficient tumors. PC-046 has growth inhibitory acti... | |||
T73620 | Poly(acrylic acid) | ||
Poly(acrylic acid) serves as an effective corrosion inhibitor for pure cast aluminium in acidic environments through its adsorption onto the metal's surface. Additionally, this compound functions as an excipient within t... | |||
T38844 | MK-8245 Trifluoroacetate | ||
MK-8245 trifluoroacetate is a phenoxy piperidine isoxazole derivative functioning as a potent, liver-targeting stearoyl-CoA desaturase (SCD) inhibitor, demonstrating significant anti-diabetic and anti-dyslipidemic effect... | |||
T64692 | AMY-101 acetate | ||
Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exe... | |||
T35890 | Pentosidine | ||
Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditi... | |||
T37880 | OPC-167832 | ||
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-16... | |||
T36308 | PF-06843195 | ||
PF-06843195 is a selective PI3Kα inhibitor, demonstrating potent activity with an IC50 of 18 nM in Rat1 fibroblasts and Kis for PI3Kα and PI3Kδ less than 0.018 nM and 0.28 nM, respectively, in biochemical kinase assays. ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3875 | CLINODISIDE A | Others | |
Clinodiside A in rats with one compartment open model into the body, rapid distribution, elimination rate. | |||
T3S0057 | Dihydrochelerythrine | 12,13-Dihydrochelerythrine | Antifungal |
1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ... | |||
T4685 | INOSINIC ACID | Inosine 5′-monophosphate,IMP,I-5'-P | Endogenous Metabolite |
Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the... | |||
TN2080 | Pinoresinol | (+)-Pinoresinol | Apoptosis , NF-κB , CDK , p53 |
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st... | |||
T6S2227 | Spinosin | Flavoayamenin | Others |
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato... | |||
T82032 | Isoglobotriaose | Gala-3Galb-4Glc | |
Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobot... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04268 | NUDC Protein, Human, Recombinant (His) | Human | HEK293 |
NUDC (Nuclear Distribution C, Dynein Complex Regulator) is a Protein Coding gene. NUDC consists of at least 9 exons ranging from 66 bp to 266 bp in size and 8 introns from 92 bp to 2.0 kb in length, and the total genomic... | |||
TMPY-01460 | ABHD4 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain... | |||
TMPY-04165 | FGFR3 Protein, Human, Recombinant (His) | Human | HEK293 |
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ... | |||
TMPY-01694 | Clusterin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot... | |||
TMPY-01691 | Clusterin Protein, Human, Recombinant (CLU34, His) | Human | HEK293 |
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot... | |||
TMPY-00341 | FGFR3 Protein, Human, Recombinant (alpha IIIb, His) | Human | HEK293 |
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ... | |||
TMPY-01736 | COX-2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox... | |||
TMPY-06034 | FGFR1 Protein, Human, Recombinant (beta (IIIb), His) | Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i... | |||
TMPY-02112 | FGFR4 Protein, Human, Recombinant (His) | Human | HEK293 |
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque... | |||
TMPY-01477 | MMP-2 Protein, Human, Recombinant | Human | HEK293 |
Matrix Metalloproteinase-2 (MMP-2) is an enzyme that degrades components of the extracellular matrix and thus plays a pivotal role in cell migration during physiological and pathological processes. MMP-2 expression is de... | |||
TMPY-06036 | FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) | Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i... | |||
TMPY-01011 | FGFR1 Protein, Human, Recombinant (His) | Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i... | |||
TMPY-00720 | Contactin 1 Protein, Human, Recombinant (His) | Human | HEK293 |
Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2 (TAG-1), Contactin-3... | |||
TMPH-03090 | SCP alpha chain Protein, Penaeus sp., Recombinant (His & Myc & SUMO) | Penaeus sp. | E. coli |
Like parvalbumins, SCP's seem to be more abundant in fast contracting muscles, but no functional relationship can be established from this distribution. | |||
TMPH-00033 | ASFV (strain Ba71V) p30 Protein (His) | ASFV | E. coli |
Modifies the subcellular distribution of heterogeneous nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate HNRNPK functions related to processing and export of mRNAs during ASFV infection. | |||
TMPH-01752 | Nestin/NES Protein, Human, Recombinant (His) | Human | Yeast |
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cell... | |||
TMPK-01222 | APLN Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized... | |||
TMPY-02133 | Carbonic Anhydrase VB Protein, Human, Recombinant (His) | Human | E. coli |
Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, ... | |||
TMPK-01193 | GPRC5D Protein-VLP, Mouse, Recombinant | Mouse | HEK293 |
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GP... | |||
TMPJ-00580 | ZWINT Protein, Human, Recombinant (His) | Human | E. coli |
ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex spec... | |||
TMPK-00223 | Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 ... | |||
TMPK-00405 | IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated | Human | HEK293 |
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restr... | |||
TMPY-00587 | GABARAP Protein, Human, Recombinant (His & MBP) | Human | E. coli |
The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in... | |||
TMPK-01236 | APLN Protein, Human, Recombinant (hFc) | Human | HEK293 |
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized... | |||
TMPY-03449 | CPNE1 Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
Copine I, also known as CPN1, is a member of the copine family. Copine I is a calcium-dependent membrane-binding protein which has a wide tissue distribution. Calcium-dependent membrane-binding proteins may regulate mo... | |||
TMPY-03265 | CPNE1 Protein, Human, Recombinant (SUMO) | Human | Baculovirus-Insect Cells |
Copine I, also known as CPN1, is a member of the copine family. Copine I is a calcium-dependent membrane-binding protein which has a wide tissue distribution. Calcium-dependent membrane-binding proteins may regulate mo... | |||
TMPK-00838 | IGFBP-2 Protein, Human, Recombinant (His) | Human | HEK293 |
Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a de... | |||
TMPK-00528 | GPRC5D Protein-VLP, Cynomolgus, Recombinant | Cynomolgus | HEK293 |
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GP... | |||
TMPJ-01291 | CPNE1 Protein, Human, Recombinant (His) | Human | E. coli |
Copine-1(CPNE1) encodes a calcium-dependent protein which belongs to the copine family. CPNE1contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, CPNE1 does not co... | |||
TMPY-03302 | TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue dis... | |||
TMPY-03604 | VAMP3 Protein, Human, Recombinant (His) | Human | E. coli |
VAMP3, also known as cellubrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components... | |||
TMPJ-00613 | CD47 Protein, Rhesus macaque, Recombinant (hFc) | Rhesus macaque | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an... | |||
TMPJ-00212 | CD47 Protein, Human, Recombinant (mFc) | Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an... | |||
TMPK-00549 | IGFBP-2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a de... | |||
TMPY-03374 | TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc) | Human,Cynomolgus | HEK293 |
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue dis... | |||
TMPJ-00209 | CD47 Protein, Human, Recombinant (Avi & His), Biotinylated | Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an... | |||
TMPJ-00208 | CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an... | |||
TMPY-03969 | SUSD4 Protein, Human, Recombinant (mFc) | Human | HEK293 |
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ... | |||
TMPY-03456 | SRFBP1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in th... | |||
TMPY-02277 | Carbonic Anhydrase 7 Protein, Human, Recombinant (His) | Human | E. coli |
Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family... | |||
TMPY-00471 | INSL4 Protein, Human, Recombinant (His) | Human | HEK293 |
INSL4 (Insulin-Like 4) is a Protein Coding gene. An important paralog of this gene is RLN1. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary st... | |||
TMPJ-01190 | SPESP1 Protein, Human, Recombinant (His) | Human | Human Cells |
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lo... | |||
TMPY-00584 | TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue dis... | |||
TMPY-05041 | TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc) | Mouse | HEK293 |
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue dis... | |||
TMPY-04759 | CAMKIV Protein, Mouse, Recombinant | Mouse | Baculovirus-Insect Cells |
Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme i... | |||
TMPY-04478 | IP6K1/IHPK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
IP6K1 (Inositol Hexakisphosphate Kinase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. IHPK1 is an inositol hexaphosphate kinase (IHPK) protein that belongs to the inositol phosph... | |||
TMPY-03118 | ORM2 Protein, Human, Recombinant (His) | Human | HEK293 |
ORM2 belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, ... | |||
TMPY-00729 | Cystatin D Protein, Human, Recombinant (His) | Human | HEK293 |
Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stef... | |||
TMPY-01551 | Serpin B8 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi... | |||
TMPY-00517 | LSP1 Protein, Human, Recombinant (His) | Human | HEK293 |
LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regula... | |||
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Cat No. | Product Name | ||
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L2300 | Ion Channel Inhibitor Library | 931 compounds | |
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; |