Home Tools
Log in
Cart

Search Result

Search Results for " distribution "

Targets

50

Compounds

6

Natural Products

133

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T2225 4-Hydroxyantipyrine COX
4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.
T35337L Teduglutide acetate Glucagon Receptor
Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy. Teduglutide acetate partially restores small intestinal epithelial function through an altered distribution of claudin-10, facilitati...
T9897 7-Methoxy-1-naphthaleneacetic acid Others
7-Methoxy-1-naphthaleneacetic acid is an inhibitor of auxin action in plants. 7-Methoxy-1-naphthaleneacetic acid inhibits polar auxin transport and tropic responses associated with asymmetric auxin distribution in Arabid...
T14835 BTRX-335140 CYM-53093 Opioid Receptor
BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. BTRX-335140...
T13247 UK-101 UK101,UK 101 Proteasome
UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM. UK-101 has a 144-fold and 10-fold higher affinity for β1i ...
T1083L Theophylline monohydrate Quibron HDAC , PDE , Adenosine Receptor
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ...
T34166 PROTAC_ERRalpha
PROTAC_ERRalpha is a proteolysis targeting chimeras (PROTAC) which provides broad tissue distribution and knockdown of the targeted ERRalpha protein in tumor xenografts.
T33392 MIP-1095 I-123 123-I-MIP-1095,(123I)MIP 1095
MIP-1095 I-123, as a radiotracer, is under investigation in clinical trial NCT00712829 (Evaluating the Safety, Pharmacokinetics, Tissue Distribution, Metabolism and Dosimetry of Two Prostate Cancer Imaging Agents).
T24924 Umibecestat HCl (1387560-01-1 free base) CNP 520,Umibecestat HCl,Umibecestat hydrochloride,CNP520,CNP-520
Umibecestat is a beta-secretase inhibitor. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies.
T32082 Histidyl-aspartyl-glutamyl-leucine His-asp-glu-leu,Hdel sequence
HDEL intracellular distribution is characteristic of plant endoplasmic reticulum (ER).
T26230 Stilbamidine dihydrochloride NSC 35605,NCI 174
Stilbamidine dihydrochloride is a blocker of neuromuscular transmission and axonal conduction used to study the distribution of the drug in the organs and tissues of rats following intravenous injection.
T82238 HAPSBC
HAPSBC, an S-benzyl iron chelator, modulates the intracellular distribution of ^59Fe [1].
T14289 Anguizole Others
Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B. It demonstrates its potency with an IC50 value, highlighting its specific target ac...
T16993 Taribavirin Others
Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cel...
T29154 WB403 WB-403,WB 403
WB403 is a TGR5 activator. WB403 significantly decreases fasting blood glucose, postprandial blood glucose and HbA1c, improves glucose tolerance in type 2 diabetic mice. WB403 increases pancreatic β-cells and restores th...
T13862L Recilisib sodium Brand name: Ex-RAD,ON 01210.Na,ON01210,ON-01210
Recilisib, also known as ON 01210.Na, is a radioprotectant, which modifys cell cycle distribution patterns in cancer cells subjected to radiation therapy, and it has been identified as a potential candidate for radiation...
T37290 Resolvin D3 methyl ester
Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cle...
T16992 Taribavirin hydrochloride Others
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin hydrochloride is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distr...
T30118 Arbaclofen placarbil XP 19986,XP19986,XP-19986
Arbaclofen placarbil( XP19986) is a GABA(B) receptor agonist.Arbaclofen Placarbil is a novel R-baclofen prodrug with improved absorption, distribution, metabolism, and elimination properties compared to R-baclofen. And i...
TP1529 Galanin (1-19), human
Galanin (1-19), human, represents the fragment encompassing amino acids 1 to 19 of the human galanin neuropeptide. Galanin (GAL) is known for its extensive distribution and multifaceted biological roles, such as regulati...
T75381 Bodipy TMR-X muscimol
Bodipy TMR-X muscimol, a Bodipy-labeled muscimol (Ex=543 nm, Em=572 nm), acts as a GABAA agonist. This compound is utilized for visualizing the distribution of reversible brain inactivations [1].
T76369 CEDAEVFKDSMVPGEK
CEDAEVFKDSMVPGEK, the peptide sequence corresponding to the rat vanilloid receptor subtype 1 (VR1), facilitates the detection and mapping of VR1 distribution [1].
T75355 LtIA-F
LtIA-F, a novel fluorescent analogue of LtIA, offers extensive pharmacological tools for investigating the structure-function relationship, distribution, and ligand-binding domain of the α3β2 nAChR subtype.
T69664 Umibecestat HCl
Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD...
T35448 10-Thiastearic Acid
Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools. 10-Thiastearic acid inhibits desaturation o...
T37463 CAY10704
CAY10704 is a potent inhibitor of hepatitis C virus (HCV) infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 μM). It displays good pharmacokinetics in m...
T76395 (Met(O)35)-Amyloid β-Protein (1-42)
(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of Aβ40. This compound is utilized in Alzheimer’s disease (AD) re...
T37169 Resolvin D2 methyl ester
Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. It evokes diverse anti-inflammatory effects which may mediate the resolution of infla...
T37168 Resolvin D1 methyl ester Resolvin D1 methyl ester
Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in a...
T72982 DPNB-ABT594
DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates nAChRs containing α4β2 subunits over the α7 subunit. It is utilized to map the distribution of nAChRs on medial habenula (MHb) neurons, thereby facilitating ...
T79438 C-Myc inhibitor 11 c-Myc
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat pharmacokinetic assays, making it suitable for cancer researc...
T37586 DMHAPC-Chol
DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B...
T73610 Lipoprotein lipase
Lipoprotein lipase, a multifunctional enzyme present in adipose tissue, heart, skeletal muscle, islets, and macrophages, plays a crucial role in normal lipoprotein metabolism, and the distribution and utilization of tiss...
T81249 Ru3 PARP
Ru3 is a poly(ADP-ribose) polymerase 1 (PARP1) inhibitor that prompts apoptosis in MCF-7 cells through various mechanisms, including DNA damage induction, inhibition of DNA repair, alteration of cell cycle distribution, ...
T82937 ATV041
ATV041, an orally active compound that combines features of Ibuprofen and nucleotide analogues, enhances the oral pharmacokinetic (PK) profile and tissue distribution, exhibiting anti-mouse hepatitis virus (MHV) activity...
T77254 Maltodextrin, dextrose equivalent 16.5-19.5
Maltodextrin (dextrose equivalent 16.5-19.5) serves as an excipient in pharmaceutical applications. Excipients, also known as pharmaceutical auxiliaries, are chemical substances utilized in drug formulation alongside act...
T37953 Sphingomyelins (buttermilk)
Sphingomyelins (SMs) are bioactive sphingolipids found in mammalian cell membranes.1SMs make up 2-15% of the total organ phospholipid population but are found at higher concentrations in the brain and myelin sheaths surr...
T68765 Spirorenone
Spirorenone is an androstadienone derivative as a highly effective aldosterone antagonist. Spirorenone is 8.6 times as potent as spironolactone, but showed a lower affinity for the mineralocorticoid receptors. In phase I...
T70914 GBR-12935 maleate
GBR-12935 is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labe...
T68356 AM-3189
AM-3189 is a potent and selective GPR40 Agonist with minimal CNS penetration, superior pharmacokinetic properties and in vivo efficacy comparable to AMG 837. AM-3189 maintains the in vivo efficacy of AMG 837 while displa...
T75329 Cellulose
Cellulose can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical...
T77228 Polyoxyethylene Sorbitan Monostearate
Polyoxyethylene Sorbitan Monostearate, an ester derived from the saturated fatty acid stearic acid (C18:0), serves multiple roles in pharmaceutical formulations, including as a surfactant, emulsifier, solubilizer, and we...
T76180 Urocortin III (human)
Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide that primarily interacts with and activates the CRF receptor type 2 (CRF-R2), showing a specific distribution in the central nervous system ...
T71252 PC-046
PC-046 is a potent tubulin-binding agent, which was originally identified for development based on selective activity in deleted in pancreas cancer locus 4 (DPC4/SMAD4) deficient tumors. PC-046 has growth inhibitory acti...
T73620 Poly(acrylic acid)
Poly(acrylic acid) serves as an effective corrosion inhibitor for pure cast aluminium in acidic environments through its adsorption onto the metal's surface. Additionally, this compound functions as an excipient within t...
T38844 MK-8245 Trifluoroacetate
MK-8245 trifluoroacetate is a phenoxy piperidine isoxazole derivative functioning as a potent, liver-targeting stearoyl-CoA desaturase (SCD) inhibitor, demonstrating significant anti-diabetic and anti-dyslipidemic effect...
T64692 AMY-101 acetate
Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exe...
T35890 Pentosidine
Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditi...
T37880 OPC-167832
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-16...
T36308 PF-06843195
PF-06843195 is a selective PI3Kα inhibitor, demonstrating potent activity with an IC50 of 18 nM in Rat1 fibroblasts and Kis for PI3Kα and PI3Kδ less than 0.018 nM and 0.28 nM, respectively, in biochemical kinase assays. ...

Compounds

4-Hydroxyantipyrine
T2225
Synonym:
Target: COX
Teduglutide acetate
T35337L
Synonym:
Target: Glucagon Receptor
7-Methoxy-1-naphthaleneacetic acid
T9897
Synonym:
Target: Others
BTRX-335140
T14835
Synonym: CYM-53093
Target: Opioid Receptor
UK-101
T13247
Synonym: UK101,UK 101
Target: Proteasome
Theophylline monohydrate
T1083L
Synonym: Quibron
Target: HDAC, PDE, Adenosine Receptor
PROTAC_ERRalpha
T34166
Synonym:
Target:
MIP-1095 I-123
T33392
Synonym: 123-I-MIP-1095,(123I)MIP 1095
Target:
Umibecestat HCl (1387560-01-1 free base)
T24924
Synonym: CNP 520,Umibecestat HCl,Umibecestat hydrochloride,CNP520,CNP-520
Target:
Histidyl-aspartyl-glutamyl-leucine
T32082
Synonym: His-asp-glu-leu,Hdel sequence
Target:
Stilbamidine dihydrochloride
T26230
Synonym: NSC 35605,NCI 174
Target:
HAPSBC
T82238
Synonym:
Target:
Anguizole
T14289
Synonym:
Target: Others
Taribavirin
T16993
Synonym:
Target: Others
WB403
T29154
Synonym: WB-403,WB 403
Target:
Recilisib sodium
T13862L
Synonym: Brand name: Ex-RAD,ON 01210.Na,ON01210,ON-01210
Target:
Resolvin D3 methyl ester
T37290
Synonym:
Target:
Taribavirin hydrochloride
T16992
Synonym:
Target: Others
Arbaclofen placarbil
T30118
Synonym: XP 19986,XP19986,XP-19986
Target:
Galanin (1-19), human
TP1529
Synonym:
Target:
Bodipy TMR-X muscimol
T75381
Synonym:
Target:
CEDAEVFKDSMVPGEK
T76369
Synonym:
Target:
LtIA-F
T75355
Synonym:
Target:
Umibecestat HCl
T69664
Synonym:
Target:
10-Thiastearic Acid
T35448
Synonym:
Target:
CAY10704
T37463
Synonym:
Target:
(Met(O)35)-Amyloid β-Protein (1-42)
T76395
Synonym:
Target:
Resolvin D2 methyl ester
T37169
Synonym:
Target:
Resolvin D1 methyl ester
T37168
Synonym: Resolvin D1 methyl ester
Target:
DPNB-ABT594
T72982
Synonym:
Target:
c-Myc inhibitor 11
T79438
Synonym:
Target: c-Myc
DMHAPC-Chol
T37586
Synonym:
Target:
Lipoprotein lipase
T73610
Synonym:
Target:
Ru3
T81249
Synonym:
Target: PARP
ATV041
T82937
Synonym:
Target:
Maltodextrin, dextrose equivalent 16.5-19.5
T77254
Synonym:
Target:
Sphingomyelins (buttermilk)
T37953
Synonym:
Target:
Spirorenone
T68765
Synonym:
Target:
GBR-12935 maleate
T70914
Synonym:
Target:
AM-3189
T68356
Synonym:
Target:
Cellulose
T75329
Synonym:
Target:
Polyoxyethylene Sorbitan Monostearate
T77228
Synonym:
Target:
Urocortin III (human)
T76180
Synonym:
Target:
PC-046
T71252
Synonym:
Target:
Poly(acrylic acid)
T73620
Synonym:
Target:
MK-8245 Trifluoroacetate
T38844
Synonym:
Target:
AMY-101 acetate
T64692
Synonym:
Target:
Pentosidine
T35890
Synonym:
Target:
OPC-167832
T37880
Synonym:
Target:
PF-06843195
T36308
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T3875 CLINODISIDE A Others
Clinodiside A in rats with one compartment open model into the body, rapid distribution, elimination rate.
T3S0057 Dihydrochelerythrine 12,13-Dihydrochelerythrine Antifungal
1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ...
T4685 INOSINIC ACID Inosine 5′-monophosphate,IMP,I-5'-P Endogenous Metabolite
Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the...
TN2080 Pinoresinol (+)-Pinoresinol Apoptosis , NF-κB , CDK , p53
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st...
T6S2227 Spinosin Flavoayamenin Others
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato...
T82032 Isoglobotriaose Gala-3Galb-4Glc
Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobot...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04268 NUDC Protein, Human, Recombinant (His) Human HEK293
NUDC (Nuclear Distribution C, Dynein Complex Regulator) is a Protein Coding gene. NUDC consists of at least 9 exons ranging from 66 bp to 266 bp in size and 8 introns from 92 bp to 2.0 kb in length, and the total genomic...
TMPY-01460 ABHD4 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain...
TMPY-04165 FGFR3 Protein, Human, Recombinant (His) Human HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-01694 Clusterin Protein, Mouse, Recombinant (His) Mouse HEK293
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His) Human HEK293
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His) Human HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-01736 COX-2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox...
TMPY-06034 FGFR1 Protein, Human, Recombinant (beta (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-02112 FGFR4 Protein, Human, Recombinant (His) Human HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-01477 MMP-2 Protein, Human, Recombinant Human HEK293
Matrix Metalloproteinase-2 (MMP-2) is an enzyme that degrades components of the extracellular matrix and thus plays a pivotal role in cell migration during physiological and pathological processes. MMP-2 expression is de...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01011 FGFR1 Protein, Human, Recombinant (His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-00720 Contactin 1 Protein, Human, Recombinant (His) Human HEK293
Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2 (TAG-1), Contactin-3...
TMPH-03090 SCP alpha chain Protein, Penaeus sp., Recombinant (His & Myc & SUMO) Penaeus sp. E. coli
Like parvalbumins, SCP's seem to be more abundant in fast contracting muscles, but no functional relationship can be established from this distribution.
TMPH-00033 ASFV (strain Ba71V) p30 Protein (His) ASFV E. coli
Modifies the subcellular distribution of heterogeneous nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate HNRNPK functions related to processing and export of mRNAs during ASFV infection.
TMPH-01752 Nestin/NES Protein, Human, Recombinant (His) Human Yeast
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cell...
TMPK-01222 APLN Protein, Mouse, Recombinant (hFc) Mouse HEK293
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized...
TMPY-02133 Carbonic Anhydrase VB Protein, Human, Recombinant (His) Human E. coli
Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, ...
TMPK-01193 GPRC5D Protein-VLP, Mouse, Recombinant Mouse HEK293
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GP...
TMPJ-00580 ZWINT Protein, Human, Recombinant (His) Human E. coli
ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex spec...
TMPK-00223 Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc) Human HEK293
Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 ...
TMPK-00405 IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated Human HEK293
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restr...
TMPY-00587 GABARAP Protein, Human, Recombinant (His & MBP) Human E. coli
The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in...
TMPK-01236 APLN Protein, Human, Recombinant (hFc) Human HEK293
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized...
TMPY-03449 CPNE1 Protein, Human, Recombinant Human Baculovirus-Insect Cells
Copine I, also known as CPN1, is a member of the copine family. Copine I is a calcium-dependent membrane-binding protein which has a wide tissue distribution. Calcium-dependent membrane-binding proteins may regulate mo...
TMPY-03265 CPNE1 Protein, Human, Recombinant (SUMO) Human Baculovirus-Insect Cells
Copine I, also known as CPN1, is a member of the copine family. Copine I is a calcium-dependent membrane-binding protein which has a wide tissue distribution. Calcium-dependent membrane-binding proteins may regulate mo...
TMPK-00838 IGFBP-2 Protein, Human, Recombinant (His) Human HEK293
Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a de...
TMPK-00528 GPRC5D Protein-VLP, Cynomolgus, Recombinant Cynomolgus HEK293
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GP...
TMPJ-01291 CPNE1 Protein, Human, Recombinant (His) Human E. coli
Copine-1(CPNE1) encodes a calcium-dependent protein which belongs to the copine family. CPNE1contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, CPNE1 does not co...
TMPY-03302 TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc) Rat HEK293
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue dis...
TMPY-03604 VAMP3 Protein, Human, Recombinant (His) Human E. coli
VAMP3, also known as cellubrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components...
TMPJ-00613 CD47 Protein, Rhesus macaque, Recombinant (hFc) Rhesus macaque Human Cells
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an...
TMPJ-00212 CD47 Protein, Human, Recombinant (mFc) Human Human Cells
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an...
TMPK-00549 IGFBP-2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a de...
TMPY-03374 TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc) Human,Cynomolgus HEK293
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue dis...
TMPJ-00209 CD47 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an...
TMPJ-00208 CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human Human Cells
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an...
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc) Human HEK293
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ...
TMPY-03456 SRFBP1 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in th...
TMPY-02277 Carbonic Anhydrase 7 Protein, Human, Recombinant (His) Human E. coli
Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family...
TMPY-00471 INSL4 Protein, Human, Recombinant (His) Human HEK293
INSL4 (Insulin-Like 4) is a Protein Coding gene. An important paralog of this gene is RLN1. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary st...
TMPJ-01190 SPESP1 Protein, Human, Recombinant (His) Human Human Cells
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lo...
TMPY-00584 TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc) Mouse HEK293
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue dis...
TMPY-05041 TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc) Mouse HEK293
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue dis...
TMPY-04759 CAMKIV Protein, Mouse, Recombinant Mouse Baculovirus-Insect Cells
Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme i...
TMPY-04478 IP6K1/IHPK1 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
IP6K1 (Inositol Hexakisphosphate Kinase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. IHPK1 is an inositol hexaphosphate kinase (IHPK) protein that belongs to the inositol phosph...
TMPY-03118 ORM2 Protein, Human, Recombinant (His) Human HEK293
ORM2 belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, ...
TMPY-00729 Cystatin D Protein, Human, Recombinant (His) Human HEK293
Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stef...
TMPY-01551 Serpin B8 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPY-00517 LSP1 Protein, Human, Recombinant (His) Human HEK293
LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regula...
------------------------ More ------------------------
NUDC Protein, Human, Recombinant (His)
TMPY-04268
Species: Human
Expression System: HEK293
ABHD4 Protein, Human, Recombinant (His)
TMPY-01460
Species: Human
Expression System: Baculovirus-Insect Cells
FGFR3 Protein, Human, Recombinant (His)
TMPY-04165
Species: Human
Expression System: HEK293
Clusterin Protein, Mouse, Recombinant (His)
TMPY-01694
Species: Mouse
Expression System: HEK293
Clusterin Protein, Human, Recombinant (CLU34, His)
TMPY-01691
Species: Human
Expression System: HEK293
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
TMPY-00341
Species: Human
Expression System: HEK293
COX-2 Protein, Human, Recombinant (His)
TMPY-01736
Species: Human
Expression System: Baculovirus-Insect Cells
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
TMPY-06034
Species: Human
Expression System: HEK293
FGFR4 Protein, Human, Recombinant (His)
TMPY-02112
Species: Human
Expression System: HEK293
MMP-2 Protein, Human, Recombinant
TMPY-01477
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
TMPY-06036
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His)
TMPY-01011
Species: Human
Expression System: HEK293
Contactin 1 Protein, Human, Recombinant (His)
TMPY-00720
Species: Human
Expression System: HEK293
SCP alpha chain Protein, Penaeus sp., Recombinant (His & Myc & SUMO)
TMPH-03090
Species: Penaeus sp.
Expression System: E. coli
ASFV (strain Ba71V) p30 Protein (His)
TMPH-00033
Species: ASFV
Expression System: E. coli
Nestin/NES Protein, Human, Recombinant (His)
TMPH-01752
Species: Human
Expression System: Yeast
APLN Protein, Mouse, Recombinant (hFc)
TMPK-01222
Species: Mouse
Expression System: HEK293
Carbonic Anhydrase VB Protein, Human, Recombinant (His)
TMPY-02133
Species: Human
Expression System: E. coli
GPRC5D Protein-VLP, Mouse, Recombinant
TMPK-01193
Species: Mouse
Expression System: HEK293
ZWINT Protein, Human, Recombinant (His)
TMPJ-00580
Species: Human
Expression System: E. coli
Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)
TMPK-00223
Species: Human
Expression System: HEK293
IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated
TMPK-00405
Species: Human
Expression System: HEK293
GABARAP Protein, Human, Recombinant (His & MBP)
TMPY-00587
Species: Human
Expression System: E. coli
APLN Protein, Human, Recombinant (hFc)
TMPK-01236
Species: Human
Expression System: HEK293
CPNE1 Protein, Human, Recombinant
TMPY-03449
Species: Human
Expression System: Baculovirus-Insect Cells
CPNE1 Protein, Human, Recombinant (SUMO)
TMPY-03265
Species: Human
Expression System: Baculovirus-Insect Cells
IGFBP-2 Protein, Human, Recombinant (His)
TMPK-00838
Species: Human
Expression System: HEK293
GPRC5D Protein-VLP, Cynomolgus, Recombinant
TMPK-00528
Species: Cynomolgus
Expression System: HEK293
CPNE1 Protein, Human, Recombinant (His)
TMPJ-01291
Species: Human
Expression System: E. coli
TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc)
TMPY-03302
Species: Rat
Expression System: HEK293
VAMP3 Protein, Human, Recombinant (His)
TMPY-03604
Species: Human
Expression System: E. coli
CD47 Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00613
Species: Rhesus macaque
Expression System: Human Cells
CD47 Protein, Human, Recombinant (mFc)
TMPJ-00212
Species: Human
Expression System: Human Cells
IGFBP-2 Protein, Cynomolgus, Recombinant (His)
TMPK-00549
Species: Cynomolgus
Expression System: HEK293
TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc)
TMPY-03374
Species: Human,Cynomolgus
Expression System: HEK293
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00209
Species: Human
Expression System: Human Cells
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPJ-00208
Species: Human
Expression System: Human Cells
SUSD4 Protein, Human, Recombinant (mFc)
TMPY-03969
Species: Human
Expression System: HEK293
SRFBP1 Protein, Human, Recombinant (His & GST)
TMPY-03456
Species: Human
Expression System: Baculovirus-Insect Cells
Carbonic Anhydrase 7 Protein, Human, Recombinant (His)
TMPY-02277
Species: Human
Expression System: E. coli
INSL4 Protein, Human, Recombinant (His)
TMPY-00471
Species: Human
Expression System: HEK293
SPESP1 Protein, Human, Recombinant (His)
TMPJ-01190
Species: Human
Expression System: Human Cells
TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc)
TMPY-00584
Species: Mouse
Expression System: HEK293
TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc)
TMPY-05041
Species: Mouse
Expression System: HEK293
CAMKIV Protein, Mouse, Recombinant
TMPY-04759
Species: Mouse
Expression System: Baculovirus-Insect Cells
IP6K1/IHPK1 Protein, Human, Recombinant (His & GST)
TMPY-04478
Species: Human
Expression System: Baculovirus-Insect Cells
ORM2 Protein, Human, Recombinant (His)
TMPY-03118
Species: Human
Expression System: HEK293
Cystatin D Protein, Human, Recombinant (His)
TMPY-00729
Species: Human
Expression System: HEK293
Serpin B8 Protein, Mouse, Recombinant (His)
TMPY-01551
Species: Mouse
Expression System: Baculovirus-Insect Cells
LSP1 Protein, Human, Recombinant (His)
TMPY-00517
Species: Human
Expression System: HEK293
Cat No. Product Name
L2300 Ion Channel Inhibitor Library

931 compounds
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
TargetMol