8bromoguanosine

8-Bromoguanosine is a brominated derivative of guanosine. It is activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects.

8-Br-GTP (tetrasodium) [8-Bromoguanosine-5'-triphosphate (tetrasodium)] is a derivative of the energy substrate GTP, utilized in protein synthesis and gluconeogenesis. It inhibits the E. coli GTPase FtsZ with a Ki value of 31.8 μM and promotes the assembly of microtubules in pig brains.

8-Br-GTP, an analog of GTP, functions as both a competitive inhibitor of FtsZ polymerization and GTPase activity (with a K i value of 31.8 μM). Moreover, it is capable of facilitating nucleic acid modification.

8-Bromoguanosine-5'-O-triphosphate, a derivative of guanosine 5'-triphosphate (GTP) - the energy substrate for protein synthesis and gluconeogenesis, acts as an inhibitor of the E. coli GTPase FtsZ with an inhibition constant (Ki) of 31.8 µM. Furthermore, at a concentration of 500 µM, it facilitates the assembly of porcine brain microtubules in a cell-free assay.