50-02-2

Dexamethasone is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory, immunosuppressive, and apoptosis-inducing activities. It inhibits the production of inflammatory miRNA-155 exosomes in macrophages, significantly reduces inflammatory cytokine expression in neutrophils and monocytes, suppresses LPS-induced macrophage inflammation, and induces autophagy. It is commonly used to induce animal models of depression, muscle atrophy, and hypertension, and holds potential in COVID-19 research.

Dexamethasone (Standard) is a reference standard for Dexamethasone, applicable for quantitative analysis, quality control, and biochemical experiments. Dexamethasone is a glucocorticoid receptor agonist and IL receptor modulator exhibiting anti-inflammatory, immunosuppressive, and apoptosis-inducing activities. It suppresses production of inflammatory iRNA-155 exosomes in macrophages, significantly reduces inflammatory cytokine expression in neutrophils and monocytes, inhibits LPS-induced macrophage inflammatory responses while inducing autophagy. It is commonly used to induce animal models of depression, muscular dystrophy, and hypertension, and shows potential in COVID-19 research.