4-hppd

Benzobicyclon is a 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor and herbicide that is spectrally active against annual grasses, sedges, and broadleaf weeds without toxicity to rice.

Mesotrione is a selective triketone herbicide

Cypyrafluone is a dual oxidase inhibitor of 4-hydroxyphenylpyruvate dioxygenase (4-HPPD), effectively blocking the production of homogentisic acid (HGA).

Iptriazopyrid (NC-656) is a triazole carboxamide herbicide that targets 4-hydroxyphenylpyruvate dioxygenase (HPPD). It exhibits a Ki value of 24.3 nM for Arabidopsis HPPD and 33.3 nM for rice HPPD. By inhibiting the synthesis of plastoquinone and carotenoids, Iptriazopyrid causes weed yellowing and death. It shows promise in research for controlling paddy field weeds such as barnyard grass.

HPPD-IN-5 (compound IV-45) is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD) with an IC50 of 0.21 μM. It is utilized as a herbicide.

Nitisinone-13C6 is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone (T1684) is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (T1684) (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (FAH) deficiency in mice when administered to pregnant dams.2It exhibits hepatoprotective effects inFAH-/-mice, such as prevention of increases in plasma levels of aspartate serine aminotransferase (AST) and conjugated bilirubin, when administration is continued following birth at a dose of 1 mg/kg. Nitisinone (T1684) (100 μg) decreases urinary excretion of homogentisate and increases urinary excretion of HPPA, HPLA, and 4-hydroxyphenylacetate in a mouse model of alkaptonuria induced by ethylnitrosourea.3Formulations containing nitisinone have been used in the treatment of hereditary tyrosinemia type 1 (HT-1).

Topramezone, a highly effective 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor, functions as a herbicide for the post-emergence eradication of broadleaf and grass weeds in corn [1].

Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana, respectively. As an herbicide, it effectively controls a wide spectrum of broadleaf and sedge weeds while demonstrating notable selectivity for rice [1].

HPPD-IN-3 (compound 25) serves as a potent inhibitor of 4-Hydroxyphenylpyruvate dioxygenase (HPPD) and exhibits greater efficacy than Mesotrione, featuring an IC50 of 10 nM [1].

HPPD-IN-4 (Compound III-29) serves as a selective HPPD inhibitor, demonstrating an IC 50 value of 0.19 μM. It is primarily utilized in research focused on high-efficiency herbicides [1].

Topramezone (Standard) is the standard substance of Topramezone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Topramezone, a highly effective 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor, functions as a herbicide for the post-emergence eradication of broadleaf and grass weeds in corn .

Nitisinone-13C6 (Standard) is a reference standard of Nitisinone-13C6 intended for quantitative analysis, quality control, and related biochemical research applications. Nitisinone-13C6 is used as an internal standard when quantitatively analyzing nitisinone by gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homovanillic acid during the tyrosine degradation pathway.