4-cholesten-3-one

7α-Hydroxy-4-cholesten-3-one is an intermediate in bile acid synthesis from cholesterol, a PXR agonist, and a biomarker for bile acid loss and diseases related to defective bile acid biosynthesis. It is also the physiological substrate for [CYP8B1].

7α-Hydroxy-4-cholesten-3-one (Standard) is a reference standard for research and analysis in studies involving 7α-Hydroxy-4-cholesten-3-one. 7α-Hydroxy-4-cholesten-3-one is a bile acid precursor that crosses the blood-brain barrier and can be used as an indicator of hepatic bile acid synthesis.7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist.7α-Hydroxy-4-cholesten-3-one can be used to study the relationship between bile acids and bile acids.7α-Hydroxy-4-cholesten-3-one is an agonist of the pregnane X receptor (PXR). 7α-Hydroxy-4-cholesten-3-one can be used to study diseases associated with defective bile acid biosynthesis.

4-Cholesten-3-One-[4-13C] (Standard) is a reference standard of 4-Cholesten-3-One-[4-13C] intended for quantitative analysis, quality control, and related biochemical research applications.

7α-Hydroxy-4-Cholesten-3-One-[13C5] (Standard) is a reference standard of 7α-Hydroxy-4-Cholesten-3-One-[13C5] intended for quantitative analysis, quality control, and related biochemical research applications.

4-Cholesten-3-One-2,2,4,6,6-D5 (Standard) is a reference standard of 4-Cholesten-3-One-2,2,4,6,6-D5 intended for quantitative analysis, quality control, and related biochemical research applications.

7-Alpha-Hydroxy-4-Cholesten-3-One-[D7] (Standard) is a reference standard of 7-Alpha-Hydroxy-4-Cholesten-3-One-[D7] intended for quantitative analysis, quality control, and related biochemical research applications.

Cholestenone is an intermediate oxidation product of cholesterol that is metabolized primarily in the liver. It can cause long-term defects in cell function. It is highly mobile in membranes and affects cholesterol turnover and efflux.