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By Target- Apoptosis
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Results for "
3-deoxyglucosone
" in TargetMol Product Catalog- Inhibitors & Agonists2
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- Recombinant Protein2
3-Deoxyglucosone
3-Deoxy-D-glucosone, 2-keto-3-Deoxyglucose
T191174084-27-9
3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGEs).3-Deoxyglucosone inactivates glutathione peroxidase and synergizes with low glucose to enhance GLP-1 secretion.3-Deoxyglucosone is used as a biomarker for diabetes mellitus.3-Deoxyglucosone has been shown to be an inhibitor of GLP-1 secretion in the presence of low glucose. 3-Deoxyglucosone inactivates glutathione oxidase, synergizes with low glucose to enhance GLP-1 secretion, and can be used as a biologic marker for diabetes.
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