17 α-propionate

Beclomethasone 17-propionate is a glucocorticoid that is the active metabolite of Beclomethasone dipropionate (BDP). As a glucocorticoid receptor (GR) agonist, 17-BMP has a 13-fold higher affinity than BDP and inhibits the production of pro-inflammatory cytokines, such as CXCL8, TNF-α, and IL-6, thus exerting an anti-inflammatory effect, and it is mainly used in the treatment of asthma and allergic rhinitis.

Clobetasone 17-Propionate (Clobetasone 17-Propionate) is a corticosteroid. Formulations containing clobetasone propionate are utilized for the treatment of conditions such as eczema, psoriasis, and lupus.

Clascoterone (CB-03-01) is a new topical and peripherally selective androgen antagonist.

Betamethasone-17-butyrate-21-propionate is a topical corticosteroid used to treat inflammatory skin diseases.

Clascoterone (Standard) is a reference standard for research and analysis in studies involving Clascoterone. Clascoterone (CB-03-01) is a new topical and peripherally selective androgen antagonist.

Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Clobetasol Propionate is the propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Specifically, clobetasol propionate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from membrane phospholipids by phospholipase A2.

Betamethasone 17-Propionate is a compound used in the study of its effects on endotoxin-induced uveitis in rats, capable of inhibiting cellular infiltration into the aqueous humor when administered topically or systemically at certain doses. However, compared to some other compounds, its inhibitory effects are relatively weaker. When administered systemically, the dosage is 1mg/kg. Additionally, in in vitro interleukin-8 (IL-8) release assays, Betamethasone 17-Propionate's suppression of IL-8 release from rat peritoneal exudate cells is less effective than that of betamethasone. Moreover, the concurrent addition of betamethasone dipropionate with Betamethasone 17-Propionate reduces the suppressive effects of betamethasone on cell infiltration and IL-1β gene expression.

Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is an effective topical glucocorticoid cream used to treat various skin diseases.

BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.

Nandrolone 17-propionate-d3 is a deuterated compound of Nandrolone 17-propionate. Nandrolone 17-propionate has a CAS number of 7207-92-3. Nandrolone propionate is an anabolic steroid action primarily consisting of androgenic and nitrogen-retentive properties.