121679-13-8

Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.

Naratriptan-D3 hydrochloride, the deuterium-labeled form of Naratriptan Hydrochloride (T6602), is a selective agonist of the 5-HT1 receptor subtype.

Naratriptan-D3 is a deuterated compound of Naratriptan. Naratriptan (T8666) has a CAS number of 121679-13-8. Naratriptan (T8666) is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.

Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydrochloride) binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.